An overview of biofilm-associated infections and the role of phytochemicals and nanomaterials in their control and prevention

T Damyanova, PD Dimitrova, D Borisova… - Pharmaceutics, 2024 - mdpi.com
Biofilm formation is considered one of the primary virulence mechanisms in Gram-positive
and Gram-negative pathogenic species, particularly those responsible for chronic infections …

[HTML][HTML] Promising strategies employing nucleic acids as antimicrobial drugs

L Moreira, NM Guimarães, RS Santos… - … Therapy-Nucleic Acids, 2024 - cell.com
Antimicrobial resistance (AMR) is a growing concern because it causes microorganisms to
develop resistance to drugs commonly used to treat infections. This results in increased …

Aggregation-induced signal amplification strategy based on peptide self-assembly for ultrasensitive electrochemical detection of melanoma biomarker

L Yuan, M Li, J Li, TF Zhu, M Dong, L Liu - Analytica Chimica Acta, 2024 - Elsevier
The detection of melanoma circulating biomarker in liquid biopsies is current under
evaluation for being potentially utilized for earlier cancer diagnosis and its metastasis …

Molybdenum Disulfide-Supported Cuprous Oxide Nanocomposite for Near-Infrared-I Light-Responsive Synergistic Antibacterial Therapy

J Li, J Li, Y Chen, P Tai, P Fu, Z Chen, PS Yap, Z Nie… - ACS …, 2024 - ACS Publications
Drug-resistant bacterial infections pose a serious threat to human health; thus, there is an
increasingly growing demand for nonantibiotic strategies to overcome drug resistance in …

Multifunctional ZnO@ DOX/ICG-LMHP Nanoparticles for Synergistic Multimodal Antitumor Activity

Z Li, J Wang, J Liu, J Yu, J Wang, H Wang… - Journal of Functional …, 2024 - mdpi.com
Multifunctional nanoparticles are of significant importance for synergistic multimodal
antitumor activity. Herein, zinc oxide (ZnO) was used as pH-sensitive nanoparticles for …

Carbon Dot-Loaded Apoptotic Vesicles Improve the Liver Kupffer Cell-Mediated Antibacterial Effect to Synergistically Alleviate Sepsis

L Xiang, Z An, X Wu, J Wang, S Cai, Y Lu, L Li… - ACS …, 2024 - ACS Publications
Sepsis is a lethal systemic inflammatory disease against infection that lacks effective
therapeutic approaches. Liver resident macrophage Kupffer cell (KC)-initiated bacterial …

Multiple bacteria recognition mechanisms and their applications

X Yin, J Shan, L Dou, Y Cheng, S Liu… - Coordination Chemistry …, 2024 - Elsevier
Throughout human history, inexhaustible emerging or re-emerging pathogenic bacteria
have never ceased to pose significant challenges to global public health. As the other side …

GSH/pH Cascade-Responsive Nanoparticles Eliminate Methicillin-Resistant Staphylococcus aureus Biofilm via Synergistic Photo-Chemo Therapy

X Kang, X Yang, F Bu, W Feng, F Liu… - … Applied Materials & …, 2024 - ACS Publications
Bacterial biofilm infection threatens public health, and efficient treatment strategies are
urgently required. Phototherapy is a potential candidate, but it is limited because of the off …

Detection of foodborne methicillin-resistant Staphylococcus aureus via fluorescence-encoded microsphere and Argonaute-mediated decoding

L Wei, M Han, Z Wang, Z Wang, S Ruan, Y Chen - Food Chemistry, 2024 - Elsevier
Molecular diagnosis of foodborne methicillin-resistant Staphylococcus aureus (MRSA) is
crucial for controlling its dissemination and ensuring food safety. However, existing genetic …

Reversible Fusion–Fission MXene Fiber-Based Microelectrodes for Target-Specific Gram-Positive and Gram-Negative Bacterium Discrimination

L Li, X Ding, S Shan, S Chen, Y Zhang… - Analytical …, 2024 - ACS Publications
Inaccurate or cumbersome clinical pathogen diagnosis between Gram-positive bacteria (G+)
and Gram-negative (G–) bacteria lead to delayed clinical therapeutic interventions …