[HTML][HTML] Harnessing role of sesamol and its nanoformulations against neurodegenerative diseases

N Singh, S Vishwas, A Kaur, H Kaur, V Kakoty… - Biomedicine & …, 2023 - Elsevier
Sesamol is a lignan of sesame seeds and a natural phenolic molecule that has emerged as
a useful medical agent. Sesamol is a non-toxic phytoconstituent, which exerts certain …

Association between manganese exposure in heavy metals mixtures and the prevalence of sarcopenia in US adults from NHANES 2011–2018

Q Huang, J Wan, W Nan, S Li, B He, Z Peng - Journal of hazardous …, 2024 - Elsevier
Environmental pollution is identified as an essential risk factor for sarcopenia. However, the
effect of manganese (Mn) exposure on the prevalence of sarcopenia is not assessed. Our …

Sesamol: A lignan in sesame seeds with potent anti-inflammatory and immunomodulatory properties

AF Majdalawieh, SH Ahari, SM Yousef… - European Journal of …, 2023 - Elsevier
Inflammation is associated with the development and progression of a plethora of diseases
including joint, metabolic, neurological, hepatic, and renal disorders. Sesamol, derived from …

Versatile photoelectrochemical biosensor based on AIS/ZnS QDs sensitized-WSe2 nanoflowers coupled with DNA nanostructure probe for “On− Off” assays of TNF-α …

Q Cai, H Li, W Dong, G Jie - Biosensors and Bioelectronics, 2023 - Elsevier
Herein, a novel multifunctional photoelectrochemical (PEC) biosensor based on AgInS 2
(AIS)/ZnS quantum dots (QDs) sensitized-WSe 2 nanoflowers and DNA nanostructure signal …

Nitrogen and sulfur co-doped carbon quantum dots as “on-off-on” fluorescence probes to detect Hg2+ and MnO4− and improving the photostability of Rhodamine B

W Gao, S Zhang, G Wang, J Cui, Y Lu, X Rong… - Analytica Chimica …, 2023 - Elsevier
Abstract Background Carbon quantum dot (CQDs) are zero-dimensional carbon
nanomaterials with a size of less than 10 nm CQDs are widely used in the field of ion …

Manganese-induced miR-125b-2-3p promotes anxiety-like behavior via TFR1-mediated ferroptosis

H Chen, J Wu, X Zhu, Y Ma, Z Li, L Lu, M Aschner… - Environmental …, 2024 - Elsevier
The toxic effects of excessive manganese (Mn) levels in the environment have led to a
severe public health concern. Ferroptosis is a newly form of cell death relying on iron …

Sesamol serves as a p53 stabilizer to relieve rheumatoid arthritis progression and inhibits the growth of synovial organoids

X Lin, T Lin, X Wang, J He, X Gao, S Lyu, Q Wang… - Phytomedicine, 2023 - Elsevier
Background Rheumatoid arthritis (RA) is an autoimmune disease known as a leading cause
of disability with considerable mortality. Developing alternative drugs and targets for RA …

[HTML][HTML] Roflumilast attenuates neuroinflammation post retinal ischemia/reperfusion injury by regulating microglia phenotype via the Nrf2/STING/NF-κB pathway

Y Guo, C Ou, N Zhang, Q Liu, K Xiong, J Yu… - International …, 2023 - Elsevier
Purpose The abnormal polarisation of microglial cells (MGs) following retinal
ischemia/reperfusion (RIR) initiates neuroinflammation and progressive death of retinal …

Ferroptosis at the crossroads of manganese-induced neurotoxicity: A retrospective study

Y Liu, S Lv, G He, C Wang, C Ou - Toxicology, 2024 - Elsevier
Manganese is an essential trace element, but overexposure can cause neurotoxicity and
subsequent neurodegenerative diseases. Ferroptosis is a form of cell death characterized …

Sesamol defends neuronal damage following cerebral ischemia/reperfusion: a crosstalk of autophagy and Notch1/NLRP3 inflammasome signaling

SM El-Sayyad, DMA El-Ella, MM Hafez… - …, 2024 - Springer
Objective Sesamol (SES) is a phenolic compound found in sesame seed oil. Several studies
have revealed its anti-inflammatory and antioxidant properties. However, its complete …