CRISPR-Cas9 modified bacteriophage for treatment of Staphylococcus aureus induced osteomyelitis and soft tissue infection

LH Cobb, JY Park, EA Swanson, MC Beard… - PLoS …, 2019 - journals.plos.org
Osteomyelitis, or bone infection, is often induced by antibiotic resistant Staphylococcus
aureus strains of bacteria. Although debridement and long-term administration of antibiotics …

[HTML][HTML] The urinary microbiome and biological therapeutics: Novel therapies for urinary tract infections

C Kenneally, CP Murphy, RD Sleator… - Microbiological …, 2022 - Elsevier
The discovery of microbial communities in the urinary tract (the urobiome) has fundamentally
altered the previous doctrine regarding urine sterility and associated urinary disorders …

Alternative therapeutic options to antibiotics for the treatment of urinary tract infections

P Loubet, J Ranfaing, A Dinh… - Frontiers in …, 2020 - frontiersin.org
Urinary tract infections (UTIs) mainly caused by Uropathogenic Escherichia coli (UPEC), are
common bacterial infections. Many individuals suffer from chronically recurring UTIs …

Phage therapy with a focus on the human microbiota

S Divya Ganeshan, Z Hosseinidoust - Antibiotics, 2019 - mdpi.com
Bacteriophages are viruses that infect bacteria. After their discovery in the early 1900s,
bacteriophages were a primary cure against infectious disease for almost 25 years, before …

A Dutch case report of successful treatment of chronic relapsing urinary tract infection with bacteriophages in a renal transplant patient

S Kuipers, MM Ruth, M Mientjes… - Antimicrobial agents …, 2019 - Am Soc Microbiol
We report a case of a 58-year-old renal transplant patient who developed a recurrent urinary
tract infection with an extended-spectrum β-lactamase (ESBL)-positive Klebsiella …

A century of clinical use of phages: a literature review

K Diallo, A Dublanchet - Antibiotics, 2023 - mdpi.com
Growing antibiotic resistance and the broken antibiotic market have renewed interest in the
use of phages, a century-old therapy that fell into oblivion in the West after two decades of …

Phage Therapy as a Novel Strategy in the Treatment of Urinary Tract Infections Caused by E. Coli

B Zalewska-Piątek, R Piątek - Antibiotics, 2020 - mdpi.com
Urinary tract infections (UTIs) are regarded as one of the most common bacterial infections
affecting millions of people, in all age groups, annually in the world. The major causative …

Case report: chronic bacterial prostatitis treated with phage therapy after multiple failed antibiotic treatments

AV Johri, P Johri, N Hoyle, L Pipia… - Frontiers in …, 2021 - frontiersin.org
Background: Chronic Bacterial Prostatitis (CBP) is an inflammatory condition caused by a
persistent bacterial infection of the prostate gland and its surrounding areas in the male …

Phage therapeutics: from promises to practices and prospectives

K Bhargava, G Nath, A Bhargava, GK Aseri… - Applied Microbiology and …, 2021 - Springer
The rise in multi-drug resistant bacteria and the inability to develop novel antibacterial
agents limits our arsenal against infectious diseases. Antibiotic resistance is a global issue …

Use of phage therapy to treat long-standing, persistent, or chronic bacterial infections

ST Abedon - Advanced Drug Delivery Reviews, 2019 - Elsevier
Viruses of bacteria–known as bacteriophages or phages–have been used clinically as
antibacterial agents for nearly 100 years. Often this phage therapy is of long-standing …