Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Hydrogels are the most relevant biochemical scaffold due to their tunable properties,
inherent biocompatibility, and similarity with tissue and cell environments. Over the past …

Stem cells and their local microenvironment, or niche, communicate through mechanical
cues to regulate cell fate and cell behaviour and to guide developmental processes. During …

Physical stimuli are essential for the function of eukaryotic cells, and changes in physical
signals are important elements in normal tissue development as well as in disease initiation …

The extracellular matrix (ECM) and its mechanical properties play an important role in
regulating the cellular responses that occur during tissue regeneration, wound healing, and …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …

Hydrogels mimic many of the physical properties of soft tissue and are widely used
biomaterials for tissue engineering and regenerative medicine. Synthetic hydrogels have …

Mechanical signals are increasingly recognized as overarching regulators of cell behaviour,
controlling stemness, organoid biology, tissue development and regeneration. Moreover …