[HTML][HTML] Severe autoimmune hemolytic anemia; epidemiology, clinical management, outcomes and knowledge gaps

FVM Mulder, D Evers, M de Haas, MJ Cruijsen… - Frontiers in …, 2023 - frontiersin.org
Autoimmune hemolytic anemia (AIHA) is an acquired hemolytic disorder, mediated by auto-
antibodies, and has a variable clinical course ranging from fully compensated low grade …

[HTML][HTML] Novel aspects of sepsis pathophysiology: NETs, plasma glycoproteins, endotheliopathy and COVID-19

M Nishibori - Journal of Pharmacological Sciences, 2022 - Elsevier
In 2016, sepsis was newly defined as life-threatening organ dysfunction caused by a
dysregulated host response to infection. Sepsis remains one of the crucial medical problems …

Complement and platelets: prothrombotic cell activation requires membrane attack complex–induced release of danger signals

M Mannes, V Pechtl, S Hafner, A Dopler… - Blood …, 2023 - ashpublications.org
Complement activation in the diseases paroxysmal nocturnal hemoglobinuria (PNH) and
atypical hemolytic uremic syndrome (aHUS) results in cytolysis and fatal thrombotic events …

Regulable Polyelectrolyte‐Surfactant Complex for Antibacterial Biomedical Catheter Coating via a Readily Scalable Route

H Yu, L Wang, Z Zhang, X Zhang… - Advanced Healthcare …, 2023 - Wiley Online Library
Constructing multifunctional surfaces is one of the practical approaches to address catheter‐
related multiple complications but is generally time‐consuming and substrate‐dependent …

C1-inhibitor treatment in patients with severe complement-mediated autoimmune hemolytic anemia

ECW de Boer, M Jalink, L Delvasto-Nuñez… - Blood …, 2023 - ashpublications.org
Complement-mediated (CM) autoimmune hemolytic anemia (AIHA) is characterized by the
destruction of red blood cells (RBCs) by autoantibodies that activate the classical …

[HTML][HTML] Intravascular hemolysis and multitreatment predict thrombosis in patients with autoimmune hemolytic anemia

B Fattizzo, M Bortolotti, JA Giannotta, A Zaninoni… - Journal of Thrombosis …, 2022 - Elsevier
Background Thrombosis may complicate autoimmune hemolytic anemia (AIHA), but its
predictors are still lacking, and no clear‐cut indications for anticoagulant prophylaxis are …

[HTML][HTML] Characterization of Three Polysaccharide-Based Hydrogels Derived from Laminaria japonica and Their Hemostatic Properties

Y Chen, J Shi, H Qiu, L You, P Xu, R Rao, M Wu, R Jia - Marine Drugs, 2024 - mdpi.com
Three Laminaria japonica polysaccharides (LJPs) extracted via water extraction (LJP-W),
acid extraction (LJP-A), and enzymatic extraction (LJP-E) were used as raw materials to be …

[HTML][HTML] Iron deficiency anemia and thrombosis risk in children—Revisiting an old hypothesis

H Kalff, H Cario, S Holzhauer - Frontiers in Pediatrics, 2022 - frontiersin.org
Iron deficiency anemia has a high prevalence in children and has repeatedly been
implicated as a risk factor for arterial and venous thrombosis. As an effective therapy for iron …

cGMP modulates hemin-mediated platelet death

AK Rohlfing, M Kremser, D Schaale… - Thrombosis …, 2024 - Elsevier
Background and aims Hemolysis is a known risk factor for thrombosis resulting in critical
limb ischemia and microcirculatory disturbance and organ failure. Intravasal hemolysis may …

[HTML][HTML] Exploring the complex network of heme-triggered effects on the blood coagulation system

S Mubeen, D Domingo-Fernández… - Journal of Clinical …, 2022 - mdpi.com
Excess labile heme, occurring under hemolytic conditions, displays a versatile modulator in
the blood coagulation system. As such, heme provokes prothrombotic states, either by …