Post-stroke cognitive impairment and dementia

NS Rost, A Brodtmann, MP Pase, SJ van Veluw… - Circulation …, 2022 - Am Heart Assoc
Poststroke cognitive impairment and dementia (PSCID) is a major source of morbidity and
mortality after stroke worldwide. PSCID occurs as a consequence of ischemic stroke …

Neuroimaging standards for research into small vessel disease—advances since 2013

M Duering, GJ Biessels, A Brodtmann, C Chen… - The Lancet …, 2023 - thelancet.com
Cerebral small vessel disease (SVD) is common during ageing and can present as stroke,
cognitive decline, neurobehavioural symptoms, or functional impairment. SVD frequently …

Pathophysiology of SARS-CoV-2: the Mount Sinai COVID-19 autopsy experience

C Bryce, Z Grimes, E Pujadas, S Ahuja, MB Beasley… - Modern …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated clinical
syndrome COVID-19 are causing overwhelming morbidity and mortality around the globe …

Cerebral amyloid angiopathy and Alzheimer disease—one peptide, two pathways

SM Greenberg, BJ Bacskai… - Nature Reviews …, 2020 - nature.com
The shared role of amyloid-β (Aβ) deposition in cerebral amyloid angiopathy (CAA) and
Alzheimer disease (AD) is arguably the clearest instance of crosstalk between …

Small vessel disease: mechanisms and clinical implications

JM Wardlaw, C Smith, M Dichgans - The Lancet Neurology, 2019 - thelancet.com
Small vessel disease is a disorder of cerebral microvessels that causes white matter
hyperintensities and several other common abnormalities (eg, recent small subcortical …

Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications

GJ Biessels, F Despa - Nature Reviews Endocrinology, 2018 - nature.com
Cognitive dysfunction is increasingly recognized as an important comorbidity of diabetes
mellitus. Different stages of diabetes-associated cognitive dysfunction exist, each with …

The neurovasculome: key roles in brain health and cognitive impairment: a scientific statement from the American Heart Association/American Stroke Association

C Iadecola, EE Smith, J Anrather, C Gu, A Mishra… - Stroke, 2023 - Am Heart Assoc
Background: Preservation of brain health has emerged as a leading public health priority for
the aging world population. Advances in neurovascular biology have revealed an intricate …

[HTML][HTML] APOE and Alzheimer's disease: from lipid transport to physiopathology and therapeutics

MA Husain, B Laurent, M Plourde - Frontiers in neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by
extracellular amyloid β (Aβ) and intraneuronal tau protein aggregations. One risk factor for …

Neurovascular and cognitive dysfunction in hypertension: epidemiology, pathobiology, and treatment

C Iadecola, RF Gottesman - Circulation research, 2019 - Am Heart Assoc
Hypertension has emerged as a leading cause of age-related cognitive impairment. Long
known to be associated with dementia caused by vascular factors, hypertension has more …

Cerebral small vessel disease: from a focal to a global perspective

A Ter Telgte, EMC Van Leijsen, K Wiegertjes… - Nature Reviews …, 2018 - nature.com
Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among
elderly individuals and is recognized as a major vascular contributor to dementia, cognitive …