Uncovering the genetic and evolutionary basis of local adaptation is a major focus of
evolutionary biology. The recent development of cost-effective methods for obtaining high …

The past fifty years have seen the development and application of numerous statistical
methods to identify genomic regions that appear to be shaped by natural selection. These …

Hypoxia occurs naturally at high-altitudes and pathologically in hypoxic solid tumors. Here,
we report that genes involved in various human cancers evolved rapidly in Tibetans and six …

Background Despite the prevalence and recurrence of polyploidization in the speciation of
flowering plants, its impacts on crop intraspecific genome diversification are largely …

In population genomics studies, accounting for the neutral covariance structure across
population allele frequencies is critical to improve the robustness of genome-wide scan …

Background Sheep were among the first animals to be domesticated. They are raised all
over the world and produce a major scale of animal-based protein for human consumption …

Brassica species, including crops such as cabbage, turnip and oilseed, display enormous
phenotypic variation. Brassica genomes have all undergone a whole-genome triplication …

The ancient biological'arms race'between microbial pathogens and humans has shaped
genetic variation in modern populations, and this has important implications for the growing …

Searching for genetic variants with unusual differentiation between subpopulations is an
established approach for identifying signals of natural selection. However, existing methods …

Wright's F-statistics, and especially F ST, provide important insights into the evolutionary
processes that influence the structure of genetic variation within and among populations …