Progression in translational research on spinal cord injury based on microenvironment imbalance

B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

Acute traumatic spinal cord injury

I Eli, DP Lerner, Z Ghogawala - Neurologic clinics, 2021 - neurologic.theclinics.com
Acute traumatic spinal cord injury (SCI) is typically associated with devastating outcomes.
The injury to the spinal cord results in damage to motor, sensory, and autonomic functions of …

The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data

JH Badhiwala, JR Wilson, CD Witiw, JS Harrop… - The Lancet …, 2021 - thelancet.com
Background Although there is a strong biological rationale for early decompression of the
injured spinal cord, the influence of the timing of surgical decompression for acute spinal …

Traumatic spinal cord injury—repair and regeneration

CS Ahuja, S Nori, L Tetreault, J Wilson, B Kwon… - …, 2017 - journals.lww.com
BACKGROUND: Traumatic spinal cord injuries (SCI) have devastating consequences for the
physical, financial, and psychosocial well-being of patients and their caregivers. Expediently …

Traumatic spinal cord injury

CS Ahuja, JR Wilson, S Nori, M Kotter… - Nature reviews Disease …, 2017 - nature.com
Traumatic spinal cord injury (SCI) has devastating consequences for the physical, social and
vocational well-being of patients. The demographic of SCIs is shifting such that an …

Mesenchymal stem cells for spinal cord injury: current options, limitations, and future of cell therapy

F Cofano, M Boido, M Monticelli, F Zenga… - International journal of …, 2019 - mdpi.com
Spinal cord injury (SCI) constitutes an inestimable public health issue. The most crucial
phase in the pathophysiological process of SCI concerns the well-known secondary injury …

Assessment and management of acute spinal cord injury: From point of injury to rehabilitation

LD Hachem, CS Ahuja, MG Fehlings - The journal of spinal cord …, 2017 - Taylor & Francis
Context: Spinal cord injury (SCI) is a devastating condition that can lead to significant
neurological impairment and reduced quality of life. Despite advancements in our …

Inflammogenesis of secondary spinal cord injury

MA Anwar, TS Al Shehabi, AH Eid - Frontiers in cellular neuroscience, 2016 - frontiersin.org
Spinal cord injury (SCI) and spinal infarction lead to neurological complications and
eventually to paraplegia or quadriplegia. These extremely debilitating conditions are major …

Stem cell therapy for spinal cord injury

L Huang, C Fu, F Xiong, C He, Q Wei - Cell transplantation, 2021 - journals.sagepub.com
Traumatic spinal cord injury (SCI) results in direct and indirect damage to neural tissues,
which results in motor and sensory dysfunction, dystonia, and pathological reflex that …

Concise review: bridging the gap: novel neuroregenerative and neuroprotective strategies in spinal cord injury

CS Ahuja, M Fehlings - Stem cells translational medicine, 2016 - academic.oup.com
Spinal cord injuries (SCIs) result in devastating lifelong disability for patients and their
families. The initial mechanical trauma is followed by a damaging secondary injury cascade …