Autophagy is a conserved, multistep pathway that degrades and recycles dysfunctional
organelles and macromolecules to maintain cellular homeostasis. Mammalian target of …

Cisplatin-based chemotherapeutic regimens are the most frequently used adjuvant
treatments for many types of cancer. However, the development of chemoresistance to …

Reactive oxygen species (ROS) are highly reactive signaling molecules that maintain redox
homeostasis in mammalian cells. Dysregulation of redox homeostasis under pathological …

Objectives Based on previous reports that ginsenosides have been shown to exert better
preventive effects on cisplatin‐induced kidney injury, the present work aims to evaluate the …

Autophagy is a dynamic process by which intracellular damaged macromolecules and
organelles are degraded and recycled for the synthesis of new cellular components. Basal …

Background Cisplatin (CP) is commonly used in the treatment of different types of cancer but
nephrotoxicity has been a major limiting factor. Therefore, the present study aimed to study …

Phytochemicals have recently received a lot of recognition for their pharmacological
activities such as anticancer, chemopreventive, and cardioprotective properties. In traditional …

Cisplatin (CP) is a broad-spectrum antineoplastic agent, used to treat many different types of
malignancies due to its high efficacy and low cost. However, its use is largely limited by …

This article recapitulates the existing in vitro and in vivo studies focusing on the effects of
neferine-an alkaloid derivative of lotus plant, in various disease models and its effects on …

The accumulation of high concentrations of cisplatin in the kidneys may cause
nephrotoxicity. Cisplatin-induced nephrotoxicity happens through the inflammation of the …