Exposure to low-dose arsenic in early life alters innate immune function in children
Early-life exposure to arsenic (As) increases risks of respiratory diseases/infections in
children. However, data on the ability of the innate immune system to combat bacterial …
children. However, data on the ability of the innate immune system to combat bacterial …
Fibroblast‐specific integrin‐alpha V differentially regulates type 17 and type 2 driven inflammation and fibrosis
JC Sciurba, RL Gieseck, N Jiwrajka… - The Journal of …, 2019 - Wiley Online Library
Fibroproliferative diseases affect a significant proportion of the world's population. Despite
this, core mechanisms driving organ fibrosis of diverse etiologies remain ill defined. Recent …
this, core mechanisms driving organ fibrosis of diverse etiologies remain ill defined. Recent …
STAT6 signaling attenuates interleukin-17-producing γδ T cells during acute Klebsiella pneumoniae infection
MH Bloodworth, DC Newcomb, DE Dulek… - Infection and …, 2016 - Am Soc Microbiol
ABSTRACT γδ T cells are prevalent at mucosal and epithelial surfaces and are a critical first
line of defense against bacterial and fungal pathogens. γδ17 cells are a subset of γδ T cells …
line of defense against bacterial and fungal pathogens. γδ17 cells are a subset of γδ T cells …
Effects of Laminaria japonica polysaccharides on airway inflammation of lungs in an asthma mouse model
R Lin, X Liu, Y Meng, M Xu, J Guo - Multidisciplinary Respiratory Medicine, 2015 - Springer
Background Asthma is a serious chronic inflammatory disease affecting 300 million people
worldwide. This aim of this study to investigate the anti-inflammatory and anti-asthmatic …
worldwide. This aim of this study to investigate the anti-inflammatory and anti-asthmatic …
AcCystatin, an immunoregulatory molecule from Angiostrongylus cantonensis, ameliorates the asthmatic response in an aluminium hydroxide/ovalbumin-induced rat …
P Ji, H Hu, X Yang, X Wei, C Zhu, J Liu, Y Feng… - Parasitology …, 2015 - Springer
Epidemiological surveys have demonstrated that helminth infections are negatively related
to atopic diseases, including asthma. Defining and characterising specific helminth …
to atopic diseases, including asthma. Defining and characterising specific helminth …
[HTML][HTML] Serum IL-17 and IL-6 increased accompany with TGF-β and IL-13 respectively in ulcerative colitis patients
JS Feng, Z Yang, YZ Zhu, Z Liu, CC Guo… - International journal of …, 2014 - ncbi.nlm.nih.gov
Purposes: To explorer the serum level of pro-and anti-inflammatory cytokines in the patients
of ulcerative colitis and irritable bowel disease. And analyze the correlation between the …
of ulcerative colitis and irritable bowel disease. And analyze the correlation between the …
Targeting tumour necrosis factor receptor 1 assembly reverses Th17-mediated colitis through boosting a Th2 response
Objective The soluble preligand assembly domain (PLAD) of tumour necrosis factor receptor
1 (TNFR1) interferes with receptor trimerisation to block downstream signalling, and …
1 (TNFR1) interferes with receptor trimerisation to block downstream signalling, and …
Immunological biomarkers improve the accuracy of clinical risk models of infection in the acute phase of ischemic stroke
D Salat, A Penalba, T García-Berrocoso… - Cerebrovascular …, 2013 - karger.com
Infection is an independent risk factor for adverse outcome in stroke patients. The risk of
developing an infection in this setting is partly related to a stroke-induced …
developing an infection in this setting is partly related to a stroke-induced …
The roles of ADAM33, ADAM28, IL-13 and IL-4 in the development of lung injuries in children with lethal non-pandemic acute infectious pneumonia
E Baurakiades, VH Costa Jr, SM Raboni… - Journal of Clinical …, 2014 - Elsevier
Abstract Background ADAM28, ADAM33, IL-13, IL-4 and other cytokines (IL-6 and IL-10)
seem to play important roles in the persistence and maintenance of acute inflammatory …
seem to play important roles in the persistence and maintenance of acute inflammatory …
CD8α+ CD11c+ extracellular vesicles in the lungs control immune homeostasis of the respiratory tract via TGF-β1 and IL-10
S Wan, S Wang, L Weng, G Zhang, Z Lin… - The Journal of …, 2018 - journals.aai.org
The immune balance of the respiratory tract is strictly regulated. Extracellular vesicles (EVs)
have been reported to participate in maintaining the immune balance in the intestinal tract …
have been reported to participate in maintaining the immune balance in the intestinal tract …