[HTML][HTML] IL-13 protects from C. difficile colitis
Objectives Clostridioides difficile infection (CDI) is the leading hospital-acquired infection in
North America. We have previously discovered that antibiotic disruption of the gut microbiota …
North America. We have previously discovered that antibiotic disruption of the gut microbiota …
HtrA2 suppresses autoimmune arthritis and regulates activation of STAT3
SH Lee, YM Moon, HB Seo, SY Kim, EK Kim, J Yi… - Scientific Reports, 2016 - nature.com
Rheumatoid arthritis (RA) is an autoimmune disease that is related to the induction of T
helper (Th) 17 cells, which secrete interleukin-17, and activation of the signal transducer and …
helper (Th) 17 cells, which secrete interleukin-17, and activation of the signal transducer and …
STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV …
DE Dulek, DC Newcomb, S Toki, K Goliniewska… - Journal of …, 2014 - Am Soc Microbiol
Immune-mediated lung injury is a hallmark of lower respiratory tract illness caused by
respiratory syncytial virus (RSV). STAT4 plays a critical role in CD4+ Th1 lineage …
respiratory syncytial virus (RSV). STAT4 plays a critical role in CD4+ Th1 lineage …
Photoimmunology and multiple sclerosis
F Marsh-Wakefield, SN Byrne - Emerging and Evolving Topics in Multiple …, 2015 - Springer
The ultraviolet (UV) radiation contained in sunlight is a powerful immune suppressant. While
exposure to UV is best known for its ability to cause skin cancer, it is also associated with …
exposure to UV is best known for its ability to cause skin cancer, it is also associated with …
Transmissible Plasmid Containing Salmonella enterica Heidelberg Isolates Modulate Cytokine Production During Early Stage of Interaction with Intestinal Epithelial …
The variation in cytokine production during bacterial invasion of human intestinal epithelial
cells (IECs) is a contributing factor for progression of the infection. A few Salmonella enterica …
cells (IECs) is a contributing factor for progression of the infection. A few Salmonella enterica …
Is IL-1β inhibition the next therapeutic target in asthma?
RS Peebles - Journal of Allergy and Clinical Immunology, 2017 - jacionline.org
In both the May issue and this month's issue of the Journal, there are 2 clinical studies that
are related by the finding of neutrophils in the airway and the identification of increased …
are related by the finding of neutrophils in the airway and the identification of increased …
Hyperglycemia results in decreased immune cell infiltration and increased viral load in the lung in a mouse model of RSV infection
F Khodakhah, A Tahamtan, M Marzban, A Shadab… - Cytokine, 2021 - Elsevier
Respiratory Syncytial virus (RSV) infection is a feared disease in vulnerable populations
with impaired immune responses. There is currently no vaccine against RSV and young …
with impaired immune responses. There is currently no vaccine against RSV and young …
IL-13 promotes recovery from C. difficile infection
Clostridioides difficile infection (CDI) is the leading hospital-acquired infection in North
America. We have previously discovered that antibiotic disruption of the gut microbiota …
America. We have previously discovered that antibiotic disruption of the gut microbiota …
A new IRF-1–driven apoptotic pathway triggered by IL-4/IL-13 kills neonatal Th1 cells and weakens protection against viral infection
Early life immune responses are deficient in Th1 lymphocytes that compromise neonatal
vaccination. We found that IL-4 and IL-13 engage a developmentally expressed IL-4Rα/IL …
vaccination. We found that IL-4 and IL-13 engage a developmentally expressed IL-4Rα/IL …