Molecular physiology and pathophysiology of bilirubin handling by the blood, liver, intestine, and brain in the newborn

TWR Hansen, RJ Wong… - Physiological …, 2020 - journals.physiology.org
Bilirubin is the end product of heme catabolism formed during a process that involves
oxidation-reduction reactions and conserves iron body stores. Unconjugated …

The clinical syndrome of bilirubin-induced neurologic dysfunction

VK Bhutani, L Johnson-Hamerman - Seminars in Fetal and Neonatal …, 2015 - Elsevier
Clinicians have hypothesized a spectrum of minor neurologic manifestations, consistent with
neuroanatomical reports and collectively termed as a “syndrome of bilirubin-induced …

Neonatal apnea: what's new?

JM Abu‐Shaweesh, RJ Martin - Pediatric pulmonology, 2008 - Wiley Online Library
Apnea of prematurity (AOP) remains a major clinical problem in present day neonatology
that warrants frequent evaluations and imposes challenges in therapeutic strategies …

Prenatal antecedents of newborn neurological maturation

JA DiPietro, KT Kivlighan, KA Costigan… - Child …, 2010 - Wiley Online Library
Fetal neurobehavioral development was modeled longitudinally using data collected at
weekly intervals from 24 to 38 weeks gestation in a sample of 112 healthy pregnancies …

[HTML][HTML] Bilirubin induced encephalopathy

P Karimzadeh, M Fallahi, M Kazemian… - Iranian journal of …, 2020 - ncbi.nlm.nih.gov
Hyperbilirubinemia is one of the most common neonatal disorders. Delayed diagnosis and
treatment of the pathologic and progressive indirect hyperbilirubinemia lead to neurological …

Clinicopathological spectrum of bilirubin encephalopathy/kernicterus

S Das, FKH van Landeghem - Diagnostics, 2019 - mdpi.com
Bilirubin encephalopathy/kernicterus is relatively rare, but continues to occur despite
universal newborn screening. What is more interesting is the spectrum of clinical and even …

High unbound bilirubin for age: a neurotoxin with major effects on the developing brain

R Cayabyab, R Ramanathan - Pediatric research, 2019 - nature.com
Neonatal hyperbilirubinemia is one of the most frequent diagnoses made in neonates. A
high level of unconjugated bilirubin that is unbound to albumin is neurotoxic when the level …

Serial brain MRI and ultrasound findings: relation to gestational age, bilirubin level, neonatal neurologic status and neurodevelopmental outcome in infants at risk of …

K Gkoltsiou, M Tzoufi, S Counsell, M Rutherford… - Early human …, 2008 - Elsevier
AIMS: To describe cranial ultrasound (cUS) and magnetic resonance imaging (MRI) findings
in neonates at risk of kernicterus, in relation to gestational age (GA), total serum bilirubin …

Is neonatal jaundice associated with autism spectrum disorders: a systematic review

SB Amin, T Smith, H Wang - Journal of autism and developmental …, 2011 - Springer
Using guidelines of the Meta-analysis of Observational Studies in Epidemiology Group, we
systematically reviewed the literature on neonatal jaundice (unconjugated …

Unbound bilirubin and acute bilirubin encephalopathy in infants born late preterm and term with significant hyperbilirubinemia

SB Amin, S Saluja, N Kler - The Journal of pediatrics, 2024 - Elsevier
Objective To compare the association of unbound bilirubin (UB), total serum bilirubin (TSB),
and bilirubin: albumin molar ratio (BAMR) with acute bilirubin encephalopathy (ABE), as …