[HTML][HTML] Inflammation–cause or consequence of heart failure or both?
S Van Linthout, C Tschöpe - Current heart failure reports, 2017 - Springer
Abstract Purpose of Review With the intention to summarize the currently available evidence
on the pathophysiological relevance of inflammation in heart failure, this review addresses …
on the pathophysiological relevance of inflammation in heart failure, this review addresses …
[HTML][HTML] Cardiac macrophage biology in the steady-state heart, the aging heart, and following myocardial infarction
Y Ma, AJ Mouton, ML Lindsey - Translational Research, 2018 - Elsevier
Macrophages play critical roles in homeostatic maintenance of the myocardium under
normal conditions and in tissue repair after injury. In the steady-state heart, resident cardiac …
normal conditions and in tissue repair after injury. In the steady-state heart, resident cardiac …
Natural melanin/alginate hydrogels achieve cardiac repair through ROS scavenging and macrophage polarization
J Zhou, W Liu, X Zhao, Y Xian, W Wu… - Advanced …, 2021 - Wiley Online Library
The efficacy of cardiac regenerative strategies for myocardial infarction (MI) treatment is
greatly limited by the cardiac microenvironment. The combination of reactive oxygen species …
greatly limited by the cardiac microenvironment. The combination of reactive oxygen species …
Tissue resident CCR2− and CCR2+ cardiac macrophages differentially orchestrate monocyte recruitment and fate specification following myocardial injury
Rationale: Recent advancements have brought to light the origins, complexity, and functions
of tissue-resident macrophages. However, in the context of tissue injury or disease, large …
of tissue-resident macrophages. However, in the context of tissue injury or disease, large …
[HTML][HTML] Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair
FC Simões, TJ Cahill, A Kenyon… - Nature …, 2020 - nature.com
Canonical roles for macrophages in mediating the fibrotic response after a heart attack
include extracellular matrix turnover and activation of cardiac fibroblasts to initiate collagen …
include extracellular matrix turnover and activation of cardiac fibroblasts to initiate collagen …
Common risk factors for heart failure and cancer
WC Meijers, RA de Boer - Cardiovascular research, 2019 - academic.oup.com
Cardiovascular (CV) disease and cancer are the leading causes of death., Over the last
decades, it has been appreciated that both CV disease and cancer are more common in …
decades, it has been appreciated that both CV disease and cancer are more common in …
Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart
The mechanistic basis for why inflammation is simultaneously both deleterious and essential
for tissue repair is not fully understood. Recently, a new paradigm has emerged: Organs are …
for tissue repair is not fully understood. Recently, a new paradigm has emerged: Organs are …
Monocyte trafficking across the vessel wall
T Gerhardt, K Ley - Cardiovascular research, 2015 - academic.oup.com
Monocytes fundamentally contribute to immune surveillance and the inflammatory response
in immunoinflammatory diseases like atherosclerosis. Recruitment of these cells to the site …
in immunoinflammatory diseases like atherosclerosis. Recruitment of these cells to the site …
[HTML][HTML] Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt (IV) pro-drug
Therapeutic nanoparticles (TNPs) aim to deliver drugs more safely and effectively to
cancers, yet clinical results have been unpredictable owing to limited in vivo understanding …
cancers, yet clinical results have been unpredictable owing to limited in vivo understanding …
[HTML][HTML] The role of macrophages in the resolution of inflammation
S Watanabe, M Alexander, AV Misharin… - The Journal of …, 2019 - Am Soc Clin Investig
Macrophages are tissue-resident or infiltrated immune cells critical for innate immunity,
normal tissue development, homeostasis, and repair of damaged tissue. Macrophage …
normal tissue development, homeostasis, and repair of damaged tissue. Macrophage …