Abstract Phospholipase A 2 (PLA 2) cleave phospholipids preferentially at the sn-2 position,
liberating free fatty acids and lysophospholipids. They are classified into six main groups …

Since its discovery in the serum of patients with severe inflammation and in rheumatoid
arthritic fluids, the secretory phospholipase A2 of group IIA (sPLA2-IIA) has been chiefly …

The transcription factors CCAAT/enhancer binding protein (C/EBP)‐β and‐δ are key
regulators for the expression of the acute phase genes in the liver, such as complement …

Snake venom and mammalian secreted phospholipases A 2 (sPLA 2 s) have been
associated with toxic (neurotoxicity, myotoxicity, etc.), pathological (inflammation, cancer …

The activity of the [− 831;+ 103] promoter of the human cyclooxygenase‐2 gene in cultured
rabbit chondrocytes is stimulated 2.9±0.3‐fold by interleukin‐1β and this stimulation …

Secreted type IIA phospholipase A 2, which is involved in arachidonic acid release, is
abundantly produced by chondrocytes and secreted in the synovial fluids of patients affected …

Secreted phospholipases A2 is a family of small molecular weight and calcium-dependent
enzymes of which the members list is presently growing. Among these enzymes, the …

Numerous studies over the years have demonstrated changes in prostaglandin (PG) levels
in intrauterine tissues in association with labour, and PG administration has long been used …

Background Secretory phospholipase A2 group IIA (sPLA2-IIA) has been identified as a
biomarker of atherosclerosis in observational and animal studies. The protein is encoded by …

Secretory phospholipase A2 group IIA (sPLA2-IIA) is an enzyme that hydrolyzes the sn-2
ester bond in glyceroacyl phospholipids present in lipoproteins and cell membranes. As …