Ischemic stroke is a late-onset, complex polygenic disease, and it has proven difficult to
identify its genetic determinants. A new study from Iceland shows that the gene encoding …

Publisher Summary This chapter describes the epidemiology and pathogenesis of
cardiovascular disease (CVD) in women and the risk factors involved, with special emphasis …

Technological advances in molecular genetics allow rapid and sensitive identification of
genomic copy number variants (CNVs). This, in turn, has sparked interest in the function …

The aim of this study was to evaluate the prevalence of factor V Leiden (FVL), prothrombin
G20210A, methylenetetrahydrofolate reductase (MTHFR) C677T gene mutations, and …

Given that substantial genetic components have been shown in ischemic stroke,
intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH), heritability may be …

Background Several studies have studied the relationship between lipoprotein lipase (LPL)
Hind III gene polymorphism and stroke susceptibility. However, the conclusions remain …

Recent genome-wide association studies (GWASs) and their meta-analyses have identified
various genes and loci underlying the predisposition to ischemic stroke or coronary artery …

Despite recent advances in acute stroke therapy, stroke remains the leading cause of severe
disability and the third leading cause of death, after heart disease and cancer, in Western …

Objective Only few hereditary ischemic small vessel diseases of the brain (SVDB) have
been reported so far. Cerebral autosomal dominant arteriopathy with subcortical infarcts and …

The genetics of cerebrovascular disease is an area of increasing interest and advances.
During the past year there have been a number of significant discoveries in the area that …