Algorithms for protein design

S Talluri - Advances in Protein Chemistry and Structural Biology, 2022 - Elsevier
Abstract Computational Protein Design has the potential to contribute to major advances in
enzyme technology, vaccine design, receptor-ligand engineering, biomaterials …

A review on engineering of organophosphorus hydrolase (OPH) enzyme

G Farnoosh, AM Latifi - Journal of Applied Biotechnology …, 2014 - eprints.bmsu.ac.ir
Organophosphorus chemicals are compounds which have been used as pesticides and
insecticides in agriculture. They're also used as nervous agents and have raised many …

Improving the thermostability of Serratia marcescens B4A chitinase via G191V site-directed mutagenesis

Z Emruzi, S Aminzadeh, AA Karkhane… - International Journal of …, 2018 - Elsevier
Chitinases with high thermostability are important for many industrial and biotechnological
applications. This study was conducted to enhance the stability of Serratia marcescens B4A …

Stability Increase of Phenolic Acid Decarboxylase by a Combination of Protein and Solvent Engineering Unlocks Applications at Elevated Temperatures

K Myrtollari, E Calderini, D Kracher… - ACS Sustainable …, 2024 - ACS Publications
Enzymatic decarboxylation of biobased hydroxycinnamic acids gives access to phenolic
styrenes for adhesive production. Phenolic acid decarboxylases are proficient enzymes that …

Three dimensional structure prediction of panomycocin, a novel Exo-β-1, 3-glucanase isolated from Wickerhamomyces anomalus NCYC 434 and the computational …

MT Muhammed, ÇD Son, F İzgü - Computational Biology and Chemistry, 2019 - Elsevier
Panomycocin is a naturally produced potent antimycotic/antifungal protein secreted by the
yeast Wickerhamomyces anomalus NCYC 434 with an exo-β-1, 3-glucanase activity. In this …

Computational protein design of bacteriocins based on structural scaffold of aureocin A53

S Talluri - International Journal of Bioinformatics Research …, 2019 - inderscienceonline.com
Bacteriocins are highly potent anti-microbial polypeptides and proteins produced by
bacteria. They are rapidly degraded in the environment after their use, due to their …

Engineering and Design of Programmable Genome Editors

S Talluri - The Journal of Physical Chemistry B, 2022 - ACS Publications
Programmable genome editors are enzymes that can be targeted to a specific location in the
genome for making site-specific alterations or deletions. The engineering, design, and …

Prediction of protein thermostability from their primary structure: the current state and development factors

DV Grishin, MV Pokrovskaya, OV Podobed… - Biomeditsinskaya …, 2017 - pbmc.ibmc.msk.ru
The construction of proteins and peptides with desired properties, including resistance to
high temperatures, as well as optimization of their amino acid composition, is an important …

Delicate balance of electrostatic interactions and disulfide bridges in thermostability of firefly luciferase

S Karimzadeh, M Moradi, S Hosseinkhani - International journal of …, 2012 - Elsevier
The wild type Photinus pyralis luciferase does not have any disulfide bridge. Disulfide
bridges are determinant in inherent stability of protein at moderate temperatures …

[PDF][PDF] Прогнозирование термостабильности белков по их первичной структуре: современное состояние и факторы развития

ДВ Гришин, МВ Покровская, ОВ Подобед… - Биомедицинская …, 2017 - pbmc.ibmc.msk.ru
Конструирование белков и пептидов с заданными свойствами, включающими
устойчивость к высоким температурам, а также оптимизация их аминокислотного …