Depression is one of the key conditions addressed by the Mental Health Gap Action
Programme (mhGAP) of WHO that can lead to self-harm and suicide. Depression is …

The prevalence of cancer and neurodegenerative diseases, such as Alzheimer's and
Parkinson's, continues to rise worldwide, presenting a significant health burden. Despite …

A unified strategy has been developed to utilize hydrazine hydrate in asymmetric organic
synthesis by overcoming the rapid background reaction with dienone. The H-bond donor …

Alzheimer's disease is a neurodegenerative disorder that impacts memory, thinking, and
behavior, and currently, there is no effective cure available for its treatment. This study …

In the present work, chalcone and pyrazoline derivatives of dehydroacetic acid have been
synthesized using methanol as solvent. All the synthesized compounds were characterized …

One of the major features of medicinal chemistry, is the synthesis of novel compounds, and
the assessment of their biological activities for potential therapeutic applications. As a …

An electrocatalytic synthesis of 2-pyrazolines via dehydrogenative and defluorinative cross-
coupling reactions between (hetero) arylaldehyde-derived N, N-dialkylhydrazones and …

We have devised a highly diastereoselective formal [2+ 1] annulation reaction of
arylidene/alkylidine-pyrazolones with in situ-generated supported as well as standard …

Dearomatization is a fundamental chemical reaction that affords complex three-dimensional
heterocyclic frameworks. We disclose the first organocatalytic dearomatization of 5 …

A Pd‐catalyzed heterocyclization/carbonylation/arylation cascade reaction between β, γ‐
unsaturated N− Ts hydrazones and commercially available arylboronic acids as coupling …