Mutations in human SLC26A4 are a common cause of hearing loss associated with
enlarged vestibular aqueducts (EVA). SLC26A4 encodes pendrin, an anion-base exchanger …

Permanent childhood sensorineural hearing loss, is one of the most common birth defects in
developed countries. It is important to identify the aetiology of hearing loss for many reasons …

Abstract Objectives/Hypothesis: In recent years, relatively subtle inner ear anomalies have
become apparent using high‐resolution computed tomography (CT). The purpose of this …

Objective To investigate the relations of monoallelic (M1), biallelic (M2), or the absence of
mutations (M0) in SLC26A4 to inner ear morphology and hearing levels in individuals with …

While cochlear implantation (CI) technology has greatly improved over the past 40 years,
one aspect of CI that continues to pose difficulties is the variability of outcomes due to …

Pendred syndrome is an autosomal recessive disorder characterized by sensorineural
hearing impairment, presence of goiter, and a partial defect in iodide organification, which …

Hereditary sensorineural hearing loss, derived from inner ear defects, is the most common
hereditary disability with a prevalence of 1 in 1000 children, although it can be present in up …

Background Conductive hearing loss is occasionally recognized in large vestibular
aqueduct (LVA) syndrome; however, the incidence rate and the cause are not known …

Enlarged vestibular aqueduct (EVA) is one of the most commonly identified inner ear
malformations in hearing loss patients including Pendred syndrome. While biallelic …

Sulfate transporters in plants represent a family of proteins containing transmembrane
domains that constitute the catalytic part of the protein and a short linking region that joins …