Clonal hematopoiesis and measurable residual disease assessment in acute myeloid leukemia

RP Hasserjian, DP Steensma… - Blood, The Journal …, 2020 - ashpublications.org
Current objectives regarding treatment of acute myeloid leukemia (AML) include achieving
complete remission (CR) by clinicopathological criteria followed by interrogation for the …

Sequencing-based measurable residual disease testing in acute myeloid leukemia

JM Yoest, CL Shirai, EJ Duncavage - Frontiers in Cell and …, 2020 - frontiersin.org
Next generation sequencing (NGS) methods have allowed for unprecedented genomic
characterization of acute myeloid leukemia (AML) over the last several years. Further …

Innovations in conditioning and post-transplant maintenance in AML: genomically informed revelations on the graft-versus-leukemia effect

HM Murdock, VT Ho, JS Garcia - Frontiers in Immunology, 2024 - frontiersin.org
Acute Myeloid Leukemia (AML) is the prototype of cancer genomics as it was the first
published cancer genome. Large-scale next generation/massively parallel sequencing …

Molecular minimal residual disease detection in acute myeloid leukemia

CM Vonk, ASA Al Hinai, D Hanekamp, PJM Valk - Cancers, 2021 - mdpi.com
Simple Summary Although the majority of patients with acute myeloid leukemia (AML) reach
a morphologic complete remission after high-dose chemotherapy, the majority of them face …

LncRNA LINC00909 promotes cell proliferation and metastasis in pediatric acute myeloid leukemia via miR-625-mediated modulation of Wnt/β-catenin signaling

L Ma, YY Wang, P Jiang - Biochemical and Biophysical Research …, 2020 - Elsevier
Long non-coding RNAs (lncRNAs) have been shown to involve in a variety of cancers. Our
present study aimed to explore the exact roles of lncRNA LINC00909 (LINC00909) in the …

Monitoring immunoglobulin heavy chain and T‑cell receptor gene rearrangement in cfDNA as minimal residual disease detection for patients with acute myeloid …

L Zhong, J Chen, X Huang, Y Li… - Oncology …, 2018 - spandidos-publications.com
The present study aimed to examine whether monoclonal immunoglobulin heavy chain
(IGH) or T‑cell receptor (TCR) gene rearrangement in cell‑free DNA (cfDNA) may be used for …

DACT3 has a tumor‐inhibiting role in acute myeloid leukemia via the suppression of Wnt/β‐catenin signaling by DVL2

Q Gao, L Hou, H Wang, L Xun - Journal of Biochemical and …, 2022 - Wiley Online Library
Dapper antagonist of catenin‐3 (DACT3) is a new tumor‐related protein associated with a
diverse set of tumors. However, whether DACT3 plays a role in acute myeloid leukemia …

Monitoring Measurable/Minimal Residual Disease in Acute Myeloid Leukemia: Multiparametric Flow Cytometry-Based Approach

PR Tembhare - Indian Journal of Medical and Paediatric …, 2023 - thieme-connect.com
Measurable/minimal residual disease (MRD) status is the most relevant predictor of clinical
outcome in hematolymphoid neoplasms, including acute myeloid leukemia (AML). In …

[图书][B] Hematopoiesis: Biochemical, Cellular, Molecular, and Genomic Perspectives

RK Gutti - 2024 - books.google.com
This new volume discusses the widespread concerns of hematopoietic challenges in
different and emerging ways. With chapters written by faculty and researchers from …

Minimal Residual Disease (MRD) as a Prognostic Marker in Acute Myeloid Leukemia

A Choudhary, R Sharma, R Manchala, KR Rao… - …, 2024 - taylorfrancis.com
AML remains incurable four decades after its discovery. AML (t-AML) treatment remained
unchanged without any improvements in outcomes. AML is characterized by cytogenetic …