[HTML][HTML] A Compressive Review about Taxol®: History and Future Challenges
Taxol®, which is also known as paclitaxel, is a chemotherapeutic agent widely used to treat
different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to …
different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to …
Tumor metastasis: Mechanistic insights and therapeutic interventions
M Liu, J Yang, B Xu, X Zhang - MedComm, 2021 - Wiley Online Library
Cancer metastasis is responsible for the vast majority of cancer‐related deaths worldwide. In
contrast to numerous discoveries that reveal the detailed mechanisms leading to the …
contrast to numerous discoveries that reveal the detailed mechanisms leading to the …
[HTML][HTML] Extracellular vesicles: Critical players during cell migration
Cell migration is essential for the development and maintenance of multicellular organisms,
contributing to embryogenesis, wound healing, immune response, and other critical …
contributing to embryogenesis, wound healing, immune response, and other critical …
[HTML][HTML] In vitro 3D cultures to model the tumor microenvironment
F Fontana, M Marzagalli, M Sommariva, N Gagliano… - Cancers, 2021 - mdpi.com
Simple Summary Tumor stroma is known to significantly influence cancer initiation and
progression. In the last decade, 3D cell cultures have shown potential in modeling the tumor …
progression. In the last decade, 3D cell cultures have shown potential in modeling the tumor …
[HTML][HTML] Extracellular vesicle–based drug delivery in cancer immunotherapy
S Najafi, J Majidpoor, K Mortezaee - Drug Delivery and Translational …, 2023 - Springer
Extracellular vesicles (EVs) are a group of nanoscale membrane-bound organelles
including exosomes, microvesicles (MVs), membrane particles, and apoptotic bodies, which …
including exosomes, microvesicles (MVs), membrane particles, and apoptotic bodies, which …
[HTML][HTML] Therapeutic mesenchymal stem/stromal cells: value, challenges and optimization
M Najar, R Melki, F Khalife, L Lagneaux… - Frontiers in cell and …, 2022 - frontiersin.org
Cellular therapy aims to replace damaged resident cells by restoring cellular and molecular
environments suitable for tissue repair and regeneration. Among several candidates …
environments suitable for tissue repair and regeneration. Among several candidates …
Polymeric coating on β-TCP scaffolds provides immobilization of small extracellular vesicles with surface-functionalization and ZEB1-Loading for bone defect repair in …
SC Tao, XR Li, WJ Wei, ZY Wei, CR Zhang, F Wang… - Biomaterials, 2022 - Elsevier
Repair of critical-size bone defects in patients with diabetes mellitus (DM) has always been
a challenge in clinical treatment. The process of bone defect regeneration can be impaired …
a challenge in clinical treatment. The process of bone defect regeneration can be impaired …
[HTML][HTML] The role of the metabolite cargo of extracellular vesicles in tumor progression
Metabolomic reprogramming in tumor and stroma cells is a hallmark of cancer but
understanding its effects on the metabolite composition and function of tumor-derived …
understanding its effects on the metabolite composition and function of tumor-derived …
[HTML][HTML] MMP-9 as prognostic marker for brain tumours: A comparative study on serum-derived small extracellular vesicles
Simple Summary The invasive nature of brain tumours, particularly glioblastoma, severely
limits its therapy. Matrix-metalloproteinases (MMPs), enzymes involved in the degradation of …
limits its therapy. Matrix-metalloproteinases (MMPs), enzymes involved in the degradation of …
[HTML][HTML] Emerging role of extracellular vesicles and cellular communication in metastasis
A Forder, CY Hsing, J Trejo Vazquez, C Garnis - Cells, 2021 - mdpi.com
Communication between cancer cells and the surrounding stromal cells of the tumor
microenvironment (TME) plays a key role in promoting metastasis, which is the major cause …
microenvironment (TME) plays a key role in promoting metastasis, which is the major cause …