Background Wound healing is a highly coordinated process involving clot formation,
inflammatory reaction, immune response, and, finally, tissue remodeling and maturation …

Health risks of inhaled nasal toxicants were reviewed with emphasis on chemically induced
nasal lesions in humans, sensory irritation, olfactory and trigeminal nerve toxicity, nasal …

Although defensins are known to inhibit the replication of human influenza A virus (IAV) in
vitro, their in vivo expression during IAV infection is not known. Here we investigated mRNA …

The nasal mucosa is the first barrier to pathogen invasion through the respiratory tract. Few
studies have focused on nasal resistance to invasion by respiratory pathogens due to the …

Naphthalene is a ubiquitous environmental contaminant that results in dose-dependent and
tissue-, species-, and cell-selective necrosis of murine Clara cells upon exposure …

Bcl-2, an inhibitor of apoptosis, is expressed in LPS-induced metaplastic goblet cells of rat
airways. The present study investigated expression of Bcl-2 in airway mucous cells of …

The mucosal surface of the respiratory tract is a common site of entry of many viruses.
Molecular and cellular aspects of the interactions of respiratory viruses with the respiratory …

Coexposure to different airborne pollutants can be more toxic to airway epithelium than an
inhalation exposure to a single pollutant. We have previously reported that coexposure to …

Exposure to lipopolysaccharides (LPS) causes extensive neutrophilic inflammation in the
airways followed by mucous cell hyperplasia (MCH) that is sustained by the anti-apoptotic …

An in vitro model of the upper respiratory tract of the horse was developed to investigate
mechanisms of respiratory diseases. Four tissues of the upper respiratory tract of three …