The expanding regulatory mechanisms and cellular functions of circular RNAs
LL Chen - Nature reviews Molecular cell biology, 2020 - nature.com
Many protein-coding genes in higher eukaryotes can produce circular RNAs (circRNAs)
through back-splicing of exons. CircRNAs differ from mRNAs in their production, structure …
through back-splicing of exons. CircRNAs differ from mRNAs in their production, structure …
The RNA-binding protein HuR in human cancer: A friend or foe?
The RNA-binding proteins (RBPs) are critical trans factors that associate with specific cis
elements present in mRNAs whose stability and translation are subject to regulation. The …
elements present in mRNAs whose stability and translation are subject to regulation. The …
Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1
HuR influences gene expression programs and hence cellular phenotypes by binding to
hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular …
hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular …
In vitro and in vivo RNA inhibition by CD9-HuR functionalized exosomes encapsulated with miRNA or CRISPR/dCas9
Z Li, X Zhou, M Wei, X Gao, L Zhao, R Shi, W Sun… - Nano …, 2018 - ACS Publications
In vitro and in vivo delivery of RNAs of interest holds promise for gene therapy. Recently,
exosomes are considered as a kind of rational vehicle for RNA delivery, especially miRNA …
exosomes are considered as a kind of rational vehicle for RNA delivery, especially miRNA …
Understanding and targeting the disease‐related RNA binding protein human antigen R (HuR)
Altered gene expression is a characteristic feature of many disease states such as
tumorigenesis, and in most cancers, it facilitates cancer cell survival and adaptation …
tumorigenesis, and in most cancers, it facilitates cancer cell survival and adaptation …
circDCUN1D4 suppresses tumor metastasis and glycolysis in lung adenocarcinoma by stabilizing TXNIP expression
Y Liang, H Wang, B Chen, Q Mao, W Xia… - … Therapy-Nucleic Acids, 2021 - cell.com
Aberrant expression of circular RNAs (circRNAs) is involved in cancer progression through
interaction with RNA-binding proteins (RBPs). Herein, we screened circRNA expression of …
interaction with RNA-binding proteins (RBPs). Herein, we screened circRNA expression of …
m6A reader YTHDC1 modulates autophagy by targeting SQSTM1 in diabetic skin
D Liang, WJ Lin, M Ren, J Qiu, C Yang, X Wang, N Li… - Autophagy, 2022 - Taylor & Francis
Dysregulation of macroautophagy/autophagy contributes to the delay of wound healing in
diabetic skin. N6-methyladenosine (m6A) RNA modification is known to play a critical role in …
diabetic skin. N6-methyladenosine (m6A) RNA modification is known to play a critical role in …
Regulation of senescence traits by MAPKs
A phenotype of indefinite growth arrest acquired in response to sublethal damage, cellular
senescence affects normal aging and age-related disease. Mitogen-activated protein …
senescence affects normal aging and age-related disease. Mitogen-activated protein …
Cellular retinoid binding-proteins, CRBP, CRABP, FABP5: Effects on retinoid metabolism, function and related diseases
JL Napoli - Pharmacology & therapeutics, 2017 - Elsevier
Abstract Cellular binding-proteins (BP), including CRBP1, CRBP2, CRABP1, CRABP2, and
FABP5, shepherd the poorly aqueous soluble retinoids during uptake, metabolism and …
FABP5, shepherd the poorly aqueous soluble retinoids during uptake, metabolism and …
HuR as a molecular target for cancer therapeutics and immune-related disorders
M Majumder, P Chakraborty, S Mohan… - Advanced drug delivery …, 2022 - Elsevier
The control of eukaryotic gene expression occurs at multiple levels, from transcription to
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …