Spheroids and organoids are important novel players in medical and life science research.
They are gradually replacing two-dimensional (2D) cell cultures. Indeed, three-dimensional …

Patient‐derived cancer cells (PDCs) and patient‐derived xenografts (PDXs) are often used
as tumor models, but have many shortcomings. PDCs not only lack diversity in terms of cell …

Malignant tumors are one of the leading causes of death which impose an increasingly
heavy burden on all countries. Therefore, the establishment of research models that closely …

Organoid technology has provided new translational research opportunities in oncology, in
part by enabling the development of patient-representative living biobanks. Prostate cancer …

A key challenge in the clinical management and cause of treatment failure of prostate cancer
(PCa) is its molecular, cellular and clinical heterogeneity. Modelling systems that fully …

Organoid cultures offer a valuable platform for studying organ-level biology, allowing for a
closer mimicry of human physiology compared to traditional two-dimensional cell culture …

Research focused on human reproductive biology has primarily relied upon clinical samples
affording mainly descriptive studies with limited implementation of functional or mechanistic …

The increasing number of available anti-cancer drugs presents a challenge for oncologists,
who must choose the most effective treatment for the patient. Precision cancer medicine …

Prostate cancer (PCa) is the most common non-cutaneous cancer in men in Europe and is
predicted to exhibit declining mortality in the European Union (EU) due to various recent …

Prioritizing treatments for individual patients with cancer remains challenging, and
performing coclinical studies using patient-derived models in real time is often unfeasible …