Cardiovascular disease is the leading cause of death and has dramatically increased in
recent years. Continuous cardiac monitoring is particularly important for early diagnosis and …

Given the rising prevalence of cardiovascular disease worldwide and the limited therapeutic
options for severe heart failure, novel technologies that harness the regenerative capacity of …

Cardiac patches are an effective way to deliver therapeutics to the heart. However, such
procedures are normally invasive and difficult to perform. Here, we develop and test a …

Cell therapy treatment of myocardial infarction (MI) is mediated, in part, by exosomes
secreted from transplanted cells. Thus, we compared the efficacy of treatment with a mixture …

Poor functional survival of the engrafted stem cells limits the therapeutic efficacy of stem-cell-
based therapy for myocardial infarction (MI). Cardiac patch-based system for cardiac repair …

Some of the most significant leaps in the history of modern civilization—the development of
article in China, the steam engine, which led to the European industrial revolution, and the …

Pluripotent stem cells (PSCs) can undergo unlimited self-renewal and can differentiate into
all the cell types present in our body, including cardiomyocytes. Therefore, PSCs can be an …

Oxygen is critical to the survival, function and fate of mammalian cells. Oxygen tension
controls cellular behavior through metabolic programming, which in turn controls tissue …

Functional cardiac tissue engineering holds promise as a candidate therapy for myocardial
infarction and heart failure. Generation of “strong-contracting and fast-conducting” cardiac …

Morbidity and mortality from ischaemic heart disease (IHD) and heart failure (HF) remain
significant in Europe and are increasing worldwide. Patients with IHD or HF might benefit …