Migraine stands as one of the most disabling neurological conditions worldwide. It is a
disorder of great challenge to study given its heterogeneous representation, cyclic nature …

The calcitonin gene-related peptide (CGRP) is implicated in the pathogenesis of several
pain-related syndromes, including migraine. Targeting CGRP and its receptor by their …

Mutations in the lamin A/C gene (LMNA) cause dilated cardiomyopathy associated with
increased activity of ERK1/2 in the heart. We recently showed that ERK1/2 phosphorylates …

Migraine is a complex neurological disorder and a major cause of disability. A wide range of
different drug classes such as triptans, antidepressants, anticonvulsants, analgesics, and …

Background Migraine is a disorder associated with neuropeptide release, pain and
inflammation. Tau protein has recently been linked to inflammatory diseases and can be …

Migraine is a common neurological disease displaying an unusual dependence on age. For
most patients, the peak intensity of migraine headaches occurs in 20s and lasts until 40s, but …

Chemotherapy-induced peripheral neuropathy (CIPN) impacts a growing number of cancer
survivors and treatment options are limited. Histone deacetylase 6 (HDAC6) inhibitors are …

HDAC6 is predominantly found in the cytoplasm and is mainly responsible for deacetylation
of non-histone proteins including α-tubulin in microtubules, the HSP90 chaperone, cortactin …

Background Chronic migraine, a highly disabling migraine subtype, affects nearly 2% of the
general population. Understanding migraine chronification is vital for developing better …

Objective Our laboratory has recently shown that there is a decrease in neuronal complexity
in head pain processing regions in mouse models of chronic migraine‐associated pain and …