Mild behavioral impairment (MBI) is a neurobehavioral syndrome that occurs in the absence
of cognitive impairment later in life (≥ 50 years of age). MBI is widespread in the pre …

The deposition of the amyloid β-protein (Aβ) in senile plaques is one of the histopathological
hallmarks of Alzheimer's disease (AD). Aβ-plaques arise first in neocortical areas and, then …

Although beta-amyloid (Aβ) positivity has shown to be associated with higher risk of
progression to Alzheimer's disease (AD) in mild cognitive impairment (MCI), information on …

The present study aimed to explore the potential neural correlates during feedback
evaluation during decision-making under risk and ambiguity in MCI. Nineteen individuals …

Background Deficits in short-term memory (STM) binding are a distinguishing feature of
preclinical stages leading to Alzheimer's disease (AD). However, the neuroanatomical …

Pittsburgh compound B (PiB) radiotracer for positron emission tomography (PET) imaging
can bind to different types of amyloid-β plaques and blood vessels (cerebral amyloid …

Proteome profile changes in Alzheimer's disease (AD) brains have been reported. However,
it is unclear whether they represent a continuous process, or whether there is a sequential …

We aimed to investigate the relationship between spatiotemporal changes of amyloid
deposition and Alzheimer's disease (AD) profiles in cognitively normal (CN) and those with …

Objective To compare how structural MRI, fluorodeoxyglucose (FDG), and flortaucipir (FTP)
PET signals predict cognitive decline in high-amyloid vs low-amyloid participants with the …

Purpose Previously, sex and apolipoprotein E (APOE) genotype had distinct effects on the
cognitive trajectory across the Alzheimer's disease (AD) continuum. We therefore aimed to …