A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression

J Liu, D Ottaviani, M Sefta, C Desbrousses… - Nature …, 2021 - nature.com
Retinoblastoma is the most frequent intraocular malignancy in children, originating from a
maturing cone precursor in the developing retina. Little is known on the molecular basis …

[HTML][HTML] Update on pathology of retinoblastoma

L Singh, S Kashyap - International journal of ophthalmology, 2018 - ncbi.nlm.nih.gov
Retinoblastoma is caused by mutational inactivation of both alleles of the RB1 gene, which
maps to chromosome 13q14 and encodes retinoblastoma protein that acts as a tumor …

Nanoparticle-mediated gene therapy as a novel strategy for the treatment of retinoblastoma

M Mandal, I Banerjee, M Mandal - Colloids and Surfaces B: Biointerfaces, 2022 - Elsevier
Over the last two decades, nanoparticulate delivery systems have revolutionized cancer
treatment by achieving target-specific delivery, enhanced bioavailability, and improved …

Trefoil Family Factor Peptide 1—A New Biomarker in Liquid Biopsies of Retinoblastoma under Therapy

MA Busch, A Haase, E Alefeld, E Biewald, L Jabbarli… - Cancers, 2023 - mdpi.com
Simple Summary Effective management of retinoblastoma (RB), a common childhood eye
cancer, requires accurate diagnosis and monitoring during therapy. In this study, the liquid …

Long non-coding RNA XIST promotes retinoblastoma cell proliferation, migration, and invasion by modulating microRNA-191-5p/brain derived neurotrophic factor

Y Xu, Z Fu, X Gao, R Wang, Q Li - Bioengineered, 2021 - Taylor & Francis
Long non-coding RNA (lncRNA) X–inactive specific transcript (XIST) is oncogenic in multiple
cancers. Herein, the present study is aimed at delving into how XIST functions in …

Liquid biopsy for solid ophthalmic malignancies: An updated review and perspectives

A Martel, S Baillif, S Nahon-Esteve, L Gastaud… - Cancers, 2020 - mdpi.com
Simple Summary To date, there is no treatment for metastatic uveal melanoma. Identifying its
metastatic spread is essential. Liquid biopsy can identify patients at risk of metastatic spread …

[HTML][HTML] Recent progress in Retinoblastoma: Pathogenesis, Presentation, Diagnosis and Management

M Zhou, J Tang, J Fan, X Wen, J Shen, R Jia… - Asia-Pacific Journal of …, 2024 - Elsevier
Retinoblastoma, the primary ocular malignancy in pediatric patients, poses a substantial
threat to mortality without prompt and effective management. The prognosis for survival and …

Expression profiles and prognostic value of miRNAs in retinoblastoma

LEA Delsin, KB Salomao, JA Pezuk… - Journal of Cancer …, 2019 - Springer
Current cure rates for retinoblastoma (RB) are very high in developed countries.
Nonetheless, in less privileged places worldwide, delayed diagnosis and refusal to adhere …

Risk of second tumors in retinoblastoma survivors after ionizing radiation: a review

D Figueiredo, IA Marques, AS Pires, CF Cavaleiro… - Cancers, 2023 - mdpi.com
Simple Summary Retinoblastoma is the most common ocular tumor among children.
Typically, individuals with retinoblastoma are regularly monitored with diagnostic techniques …

Long intergenic non-protein coding RNA 115 (LINC00115) aggravates retinoblastoma progression by targeting microRNA miR-489-3p that downregulates 6 …

F Ji, C Dai, M Xin, J Zhang, Y Zhang, S Liu - Bioengineered, 2022 - Taylor & Francis
Long non-coding RNAs (lncRNAs) are key regulators of cancer. However, the role of long
intergenic non-protein coding RNA 115 (LINC00115) in the regulation of retinoblastoma …