Premature ovarian failure is a to some extent unknown and intricate problem with diverse
causes and clinical manifestations. The lack of ovarian sex hormones presumably is …

Androgens mediate their actions via the androgen receptor (AR), a member of the nuclear
receptor superfamily. AR-mediated androgen action is essential in male reproductive …

Thyroid hormones (THs) are well-known regulators of development and metabolism in
vertebrates. There is increasing evidence that THs are also involved in gonadal …

Androgen production by the ovary is an essential requirement for normal cyclical secretion
of estradiol but its physiological role extends to important actions on both preantral and …

MicroRNAs (miRNAs) are a class of non-coding RNAs that post-transcriptionally silence
target mRNAs. Dysregulation of miRNAs is a frequent event in several diseases, including …

Androgens, although traditionally thought to be male sex steroids, play important roles in
female reproduction, both in healthy and pathological states. This mini-review focuses on …

Polycystic ovary syndrome (PCOS) is the most common, though heterogeneous, endocrine
aberration in women of reproductive age, with high prevalence and socioeconomic costs …

Follicle-stimulating hormone receptor (FSHR) and its intracellular signaling control
mammalian follicular development and female infertility. Our previous study showed that …

The genomic actions of thyroid hormone and steroids depend upon primary interactions of
the hormones with their specific nuclear receptor proteins. Formation of nuclear co-activator …

In women, excess androgen causes polycystic ovary syndrome (PCOS), a common fertility
disorder with comorbid metabolic dysfunctions including diabetes, obesity, and nonalcoholic …