The heterogeneous and multifactorial essence of polycystic ovary syndrome (PCOS)
renders a remarkable significance to microRNAs (miRNAs). Normo-androgenic (NA) and …

The “ovarian cycle” is an exquisite and dynamic endocrine system that includes ovarian
events, hypothalamic–pituitary interactions, uterine endometrial and myometrial changes …

Androgens are essential for the normal function of mature antral follicles but also have a role
in the early stages of follicle development. Polycystic ovary syndrome (PCOS), the most …

Purpose The aim of the present systematic review and meta-analysis was to summarize
evidence on the effectiveness of testosterone supplementation for poor ovarian responders …

Background Gonadotropins induce follicular development that leads to ovulation and
luteinization. In women, the level of gonadotropins, along with the expression of their …

Cellular junctions play a critical role in structural connection and signal communication
between cells in various tissues. Although there are structural and functional varieties …

This review based on translational research predicts that the transcription factor p53 is the
key effector of all anti-acne therapies. All-trans retinoic acid (ATRA) and isotretinoin (13-cis …

Objective This study aimed to present a narrative review regarding androgen production,
androgens' role in folliculogenesis, and the available therapeutic approaches for androgen …

The circadian system is responsible for the temporal organisation of physiological functions
which, in part, involves daily cycles of hormonal activity. In this review, we analyse the …

Rhythmic events in female reproductive physiology, including ovulation, are tightly
controlled by the circadian timing system. The molecular clock, a feedback loop oscillator of …