Hormonal mechanisms regulating follicular wave dynamics II: Progesterone decreases diameter at follicle selection regardless of whether circulating FSH or LH are …
VE Gomez-León, OJ Ginther, JD Guimarães… - Theriogenology, 2020 - Elsevier
Selection of a single dominant follicle is morphologically manifested by diameter deviation
between the future dominant follicle (F1) and the future largest subordinate follicle (F2) …
between the future dominant follicle (F1) and the future largest subordinate follicle (F2) …
A review of the physiology behind letrozole applications in infertility: are current protocols optimal?
BI Rose, SE Brown - Journal of Assisted Reproduction and Genetics, 2020 - Springer
Letrozole is a targeted aromatase inhibitor which has primarily been used in post-
menopausal women with breast cancer. Recently, it has been utilized in infertile pre …
menopausal women with breast cancer. Recently, it has been utilized in infertile pre …
[HTML][HTML] Abnormal mitochondrial function and impaired granulosa cell differentiation in androgen receptor knockout mice
RS Wang, HY Chang, SH Kao, CH Kao, YC Wu… - International journal of …, 2015 - mdpi.com
In the ovary, the paracrine interactions between the oocyte and surrounded granulosa cells
are critical for optimal oocyte quality and embryonic development. Mice lacking the …
are critical for optimal oocyte quality and embryonic development. Mice lacking the …
Follicle isolation methods reveal plasticity of granulosa cell steroidogenic capacity during mouse in vitro follicle growth
Follicles are the functional unit of the ovary and several methods have been developed to
grow follicles ex vivo, which recapitulate key events of oogenesis and folliculogenesis …
grow follicles ex vivo, which recapitulate key events of oogenesis and folliculogenesis …
A plasma membrane–associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells
H Kalyanaraman, DE Casteel, SP China, S Zhuang… - Science …, 2024 - science.org
Androgen binding to the androgen receptor (AR) in the cytoplasm induces the AR to
translocate to the nucleus, where it regulates the expression of target genes. Here, we found …
translocate to the nucleus, where it regulates the expression of target genes. Here, we found …
The role of microRNAs in ovarian function and the transition toward novel therapeutic strategies in fertility preservation: from bench to future clinical application
C Alexandri, A Daniel, G Bruylants… - Human reproduction …, 2020 - academic.oup.com
BACKGROUND New therapeutic approaches in oncology have converted cancer from a
certain death sentence to a chronic disease. However, there are still challenges to be …
certain death sentence to a chronic disease. However, there are still challenges to be …
Maternal nutrient restriction impairs young adult offspring ovarian signaling resulting in reproductive dysfunction and follicle loss
Reproductive abnormalities are included as health complications in offspring exposed to
poor prenatal nutrition. We have previously shown in a rodent model that offspring born to …
poor prenatal nutrition. We have previously shown in a rodent model that offspring born to …
Androgens as double-edged swords: induction and suppression of follicular development
JX Pan, JY Zhang, ZH Ke, FF Wang, JA Barry… - Hormones, 2015 - Springer
Androgens, which are mediated via the androgen receptor (AR), play important roles in
normal follicular development and female fertility. However, just like a double-edged sword …
normal follicular development and female fertility. However, just like a double-edged sword …
MicroRNAs as new players in endocrinology
C Peng, YL Wang - Frontiers in endocrinology, 2018 - frontiersin.org
Endocrinology is the study of hormones. The term “hormone” was coined by Starling in
1905, based on the discovery of secretin (1). Hormones are traditionally defined as chemical …
1905, based on the discovery of secretin (1). Hormones are traditionally defined as chemical …