Role of ketogenic diet in neurodegenerative diseases focusing on Alzheimer diseases: The guardian angle

HM Al-Kuraishy, MS Jabir, AK Albuhadily… - Ageing Research …, 2024 - Elsevier
The ketogenic diet (KD) is a low-carbohydrate, adequate protein and high-fat diet. KD is
primarily used to treat refractory epilepsy. KD was shown to be effective in treating different …

Molecular Mechanisms of Neuroprotection by Ketone Bodies and Ketogenic Diet in Cerebral Ischemia and Neurodegenerative Diseases

J Jang, SR Kim, JE Lee, S Lee, HJ Son… - International journal of …, 2023 - mdpi.com
Ketone bodies (KBs), such as acetoacetate and β-hydroxybutyrate, serve as crucial
alternative energy sources during glucose deficiency. KBs, generated through ketogenesis …

Exploring the impacts of ketogenic diet on reversible hepatic steatosis: initial analysis in male mice

G Ravaut, A Carneiro, C Mounier - Frontiers in nutrition, 2024 - frontiersin.org
Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common chronic
liver disease. Ketogenic diet (KD), a diet with very low intake in carbohydrates, gained …

Sex-dependent effects of carbohydrate source and quantity on caspase-1 activity in the mouse central nervous system

R Valiauga, S Talley, M Khemmani… - Journal of …, 2024 - Springer
Background Mounting evidence links glucose intolerance and diabetes as aspects of
metabolic dysregulation that are associated with an increased risk of developing dementia …

The Effects of Ketogenic Diet on Brain Gene Expressions in Type 2 Diabetes Background

Q Ren, J Fu, X Duan, L Sun, Z Mu, W Liang, Y Li… - Neuroscience, 2024 - Elsevier
Type 2 diabetes mellitus (T2DM) is a major risk factor of a number of neurodegenerative
diseases (NDDs). Ketogenic diet (KD) has significant beneficial effects on glycemic control …

Polypeptide-PNP2 in Corn Cervi Pantotrichum Ameliorates Cognitive Impairment in Alzheimer's Disease Mice by Inhibiting Microglial Cell Activation

H Pei, Z He, R Du, Y Yang, S Wu, W Li, J Sheng… - Molecular …, 2024 - Springer
We isolated a polypeptide PNP2 from Corn Cervi Pantotrichum and investigated its effect
and mechanism on cognitive impairment in Alzheimer's disease (AD) mice. Morris water …

Biomaterial strategies for regulating the neuroinflammatory response

AN Galindo, DAF Rubio, MH Hettiaratchi - Materials Advances, 2024 - pubs.rsc.org
Injury and disease in the central nervous system (CNS) can result in a dysregulated
inflammatory environment that inhibits the repair of functional tissue. Biomaterials present a …

Ferroptosis: A New Strategy for Targeting Alzheimer's Disease

RR Qiang, Y Xiang, L Zhang, XY Bai, D Zhang… - Neurochemistry …, 2024 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a complex
pathogenesis, which involves the formation of amyloid plaques and neurofibrillary tangles …

Alzheimer's disease and epilepsy: Research hotspots for comorbidity in the era of global aging

X Zhou, Y Liu, Z Wu, X Zhang, H Tao - Epilepsy & Behavior, 2024 - Elsevier
Neurological conditions such as Alzheimer's disease (AD) and epilepsy share a significant
clinical overlap, particularly in the elderly, with each disorder potentiating the risk of the …

Take the bull by the horns and tackle the potential downsides of the ketogenic diet

Y Meng, J Sun, G Zhang - Nutrition, 2024 - Elsevier
The ketogenic diet (KD) is a distinctive dietary regimen known for its low-carbohydrate and
high-fat composition. Recently, it has garnered considerable interest from the scientific …