While risk scores are invaluable tools for adapted preventive strategies, a significant gap
exists between predicted and actual event rates. Additional tools to further stratify the risk of …

Atherosclerosis causes clinical disease through luminal narrowing or by precipitating
thrombi that obstruct blood flow to the heart (coronary heart disease), brain (ischemic …

Background: Relative risk reduction with statin therapy has been consistent across nearly all
subgroups studied to date. However, in analyses of 2 randomized controlled primary …

Background—Data are limited on the presence, distribution, and extent of subclinical
atherosclerosis in middle-aged populations. Methods and Results—The PESA (Progression …

Background: Although recent studies suggest that measuring coronary artery calcification
(CAC) may be superior to indirect atherosclerotic markers in predicting cardiac risk, there …

Carotid intima-media thickness (CIMT) has been shown to predict cardiovascular (CV) risk in
multiple large studies. Careful evaluation of CIMT studies reveals discrepancies in the …

Background: Early subclinical atherosclerosis has been mainly researched in carotid
arteries. The potential value of femoral arteries for improving the predictive capacity of …

Introduction Prediction of cardiovascular events improves using imaging, ie coronary
calcium score and ultrasound assessment of carotid plaque. This study analysed the …

Atherosclerotic plaque detection by carotid ultrasound provides cardiovascular disease risk
stratification. The advantages and disadvantages of two-dimensional (2D) and three …

Background and Purpose—Carotid ultrasound evaluation of intima-media thickness (IMT)
and plaque burden has been used for risk stratification and for evaluation of …