Targeting metalloenzymes for therapeutic intervention
AY Chen, RN Adamek, BL Dick, CV Credille… - Chemical …, 2018 - ACS Publications
Metalloenzymes are central to a wide range of essential biological activities, including
nucleic acid modification, protein degradation, and many others. The role of metalloenzymes …
nucleic acid modification, protein degradation, and many others. The role of metalloenzymes …
Angiotensin-I-converting enzyme and its relatives
JF Riordan - Genome biology, 2003 - Springer
Angiotensin-I-converting enzyme (ACE) is a monomeric, membrane-bound, zinc-and
chloride-dependent peptidyl dipeptidase that catalyzes the conversion of the decapeptide …
chloride-dependent peptidyl dipeptidase that catalyzes the conversion of the decapeptide …
2018 Korean Society of Hypertension Guidelines for the management of hypertension: part II-diagnosis and treatment of hypertension
The standardized techniques of blood pressure (BP) measurement in the clinic are
emphasized and it is recommended to replace the mercury sphygmomanometer by a non …
emphasized and it is recommended to replace the mercury sphygmomanometer by a non …
Ace revisited: a new target for structure-based drug design
KR Acharya, ED Sturrock, JF Riordan… - Nature Reviews Drug …, 2003 - nature.com
Current-generation angiotensin-converting enzyme (ACE) inhibitors are widely used for
cardiovascular diseases, including high blood pressure, heart failure, heart attack and …
cardiovascular diseases, including high blood pressure, heart failure, heart attack and …
Renin angiotensin aldosterone inhibition in the treatment of cardiovascular disease
CM Ferrario, AE Mullick - Pharmacological research, 2017 - Elsevier
A collective century of discoveries establishes the importance of the renin angiotensin
aldosterone system in maintaining blood pressure, fluid volume and electrolyte homeostasis …
aldosterone system in maintaining blood pressure, fluid volume and electrolyte homeostasis …
[HTML][HTML] Angiotensin-converting enzyme inhibitors induce cough
İ Yılmaz - Turkish thoracic journal, 2019 - ncbi.nlm.nih.gov
Angiotensin-converting enzyme inhibitors (ACE-I) are widely used in diseases, such as
hypertension, congestive heart failure, and myocardial infarction. Although these drugs are …
hypertension, congestive heart failure, and myocardial infarction. Although these drugs are …
Angiotensin-converting enzyme inhibitor-induced angioedema
S Bezalel, K Mahlab-Guri, I Asher, B Werner… - The American journal of …, 2015 - Elsevier
Angiotensin-converting enzyme inhibitors (ACE-I) are widely used, effective, and well-
tolerated antihypertensive agents. The mechanisms by which those agents act can cause …
tolerated antihypertensive agents. The mechanisms by which those agents act can cause …
High angiotensin-I converting enzyme (ACE) inhibitory activity of Alcalase-digested green soybean (Glycine max) hydrolysates
MA Hanafi, SN Hashim, SY Chay… - Food Research …, 2018 - Elsevier
As a protein-rich, underutilized crop, green soybean could be exploited to produce
hydrolysates containing angiotensin-I converting enzyme (ACE) inhibitory peptides. Defatted …
hydrolysates containing angiotensin-I converting enzyme (ACE) inhibitory peptides. Defatted …
2013 Korean Society of Hypertension guidelines for the management of hypertension. Part II—treatments of hypertension
Abstract Treatment strategies are provided in accordance with the level of global
cardiovascular risk, from lifestyle modification in the lower risk group to more comprehensive …
cardiovascular risk, from lifestyle modification in the lower risk group to more comprehensive …
Renin–angiotensin–aldosterone pathway modulators in chronic kidney disease: A comparative review
S Alshahrani - Frontiers in Pharmacology, 2023 - frontiersin.org
Chronic kidney disease presents a health challenge that has a complex underlying
pathophysiology, both acquired and inherited. The pharmacotherapeutic treatment options …
pathophysiology, both acquired and inherited. The pharmacotherapeutic treatment options …