Targeting NEDD8-activating enzyme for cancer therapy: developments, clinical trials, challenges and future research directions
DJ Fu, T Wang - Journal of Hematology & Oncology, 2023 - Springer
NEDDylation, a post-translational modification through three-step enzymatic cascades,
plays crucial roles in the regulation of diverse biological processes. NEDD8-activating …
plays crucial roles in the regulation of diverse biological processes. NEDD8-activating …
Insights into the role of LncRNAs and miRNAs in glioma progression and their potential as novel therapeutic targets
Simple Summary Recent research has revealed the involvement of long non-coding RNAs
(lncRNAs) and micro RNAs (miRNAs) in glioma development and advancement, suggesting …
(lncRNAs) and micro RNAs (miRNAs) in glioma development and advancement, suggesting …
Emerging trends in post-translational modification: Shedding light on Glioblastoma multiforme
Recent multi-omics studies, including proteomics, transcriptomics, genomics, and
metabolomics have revealed the critical role of post-translational modifications (PTMs) in the …
metabolomics have revealed the critical role of post-translational modifications (PTMs) in the …
[PDF][PDF] Gieleci nska
Accumulating evidence supports that both long non-coding and micro RNAs (lncRNAs and
miRNAs) are implicated in glioma tumorigenesis and progression. Poor outcome of gliomas …
miRNAs) are implicated in glioma tumorigenesis and progression. Poor outcome of gliomas …
[HTML][HTML] Importance of Autophagy Regulation in Glioblastoma with Temozolomide Resistance
YK Hwang, DH Lee, EC Lee, JS Oh - Cells, 2024 - mdpi.com
Glioblastoma (GBM) is the most aggressive and common malignant and CNS tumor,
accounting for 47.7% of total cases. Glioblastoma has an incidence rate of 3.21 cases per …
accounting for 47.7% of total cases. Glioblastoma has an incidence rate of 3.21 cases per …
Advance in Targeted Cancer Therapy and Mechanisms of Resistance
PMK Tang, D Zhang - International Journal of Molecular Sciences, 2023 - mdpi.com
IJMS | Free Full-Text | Advance in Targeted Cancer Therapy and Mechanisms of Resistance
Next Article in Journal Involvement of CONSTANS-like Proteins in Plant Flowering and Abiotic …
Next Article in Journal Involvement of CONSTANS-like Proteins in Plant Flowering and Abiotic …
Prognostic prediction and immune checkpoint profiling in glioma patients through neddylation-associated features
J Qi, L Li, B Gao, K Dai, K Shen, X Wu, H Li, Z Yu… - Gene, 2024 - Elsevier
Background Gliomas are the most common primary malignant tumours of the central
nervous system, and neddylation may be a potential target for the treatment of gliomas. Our …
nervous system, and neddylation may be a potential target for the treatment of gliomas. Our …
[PDF][PDF] Insights into the Role of lncRNAs and miRNAs in Glioma Progression and Their Potential as Novel Therapeutic Targets. Cancers 2023, 15, 3298. h ps
Accumulating evidence supports that both long non-coding and micro RNAs (lncRNAs and
miRNAs) are implicated in glioma tumorigenesis and progression. Poor outcome of gliomas …
miRNAs) are implicated in glioma tumorigenesis and progression. Poor outcome of gliomas …
Neddylation-related gene signature predicts the prognosis and is associated with immune infiltration of glioma
Z Jiang, W Yin, G Tang, Y Guo, HL Huang, Z Wang… - 2024 - researchsquare.com
Background Glioma is the most prevalent malignant tumor that originates from central
nervous system. Neddylation, a post-translational modification similar to ubiquitination, is …
nervous system. Neddylation, a post-translational modification similar to ubiquitination, is …
Investigating the role of JARID2 in treatment resistance in glioblastoma
MMH Al-Jabri - 2023 - etheses.whiterose.ac.uk
Glioblastoma (GBM) is the deadliest primary brain tumour in adults with a median survival of
14-20 months from initial diagnosis. Despite aggressive treatment involving maximal …
14-20 months from initial diagnosis. Despite aggressive treatment involving maximal …