[HTML][HTML] Cytokine tuning of intestinal epithelial function
C Andrews, MH McLean, SK Durum - Frontiers in immunology, 2018 - frontiersin.org
The intestine serves as both our largest single barrier to the external environment and the
host of more immune cells than any other location in our bodies. Separating these potential …
host of more immune cells than any other location in our bodies. Separating these potential …
[HTML][HTML] The effects and mechanisms of cyanidin-3-glucoside and its phenolic metabolites in maintaining intestinal integrity
J Tan, Y Li, DX Hou, S Wu - Antioxidants, 2019 - mdpi.com
Cyanidin-3-glucoside (C3G) is a well-known natural anthocyanin and possesses antioxidant
and anti-inflammatory properties. The catabolism of C3G in the gastrointestinal tract could …
and anti-inflammatory properties. The catabolism of C3G in the gastrointestinal tract could …
[HTML][HTML] Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
AD Giannou, J Kempski, AM Shiri, J Lücke, T Zhang… - Immunity, 2023 - cell.com
During metastasis, cancer cells invade, intravasate, enter the circulation, extravasate, and
colonize target organs. Here, we examined the role of interleukin (IL)-22 in metastasis …
colonize target organs. Here, we examined the role of interleukin (IL)-22 in metastasis …
[HTML][HTML] m6A binding protein YTHDF2 in cancer
X Chen, X Zhou, X Wang - Experimental hematology & oncology, 2022 - Springer
YT521-B homology domain family member 2 (YTHDF2) is an N6-methyladenosine (m6A)-
binding protein that was originally found to regulate the stability of mRNA. Growing evidence …
binding protein that was originally found to regulate the stability of mRNA. Growing evidence …
[HTML][HTML] TNF receptor associated factor 2 (TRAF2) signaling in cancer
D Siegmund, J Wagner, H Wajant - Cancers, 2022 - mdpi.com
Simple Summary Tumor necrosis factor (TNF) receptor associated factor-2 (TRAF2) is an
intracellular adapter protein with E3 ligase activity, which interacts with a plethora of other …
intracellular adapter protein with E3 ligase activity, which interacts with a plethora of other …
[HTML][HTML] Epithelium-autonomous NAIP/NLRC4 prevents TNF-driven inflammatory destruction of the gut epithelial barrier in Salmonella-infected mice
The gut epithelium is a critical protective barrier. Its NAIP/NLRC4 inflammasome senses
infection by Gram-negative bacteria, including Salmonella Typhimurium (S. Tm) and …
infection by Gram-negative bacteria, including Salmonella Typhimurium (S. Tm) and …
[HTML][HTML] Bacterial translocation as inflammatory driver in Crohn's disease
R Linares, R Francés, A Gutiérrez… - Frontiers in Cell and …, 2021 - frontiersin.org
Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract
responsible for intestinal lesions. The multifactorial etiology attributed to CD includes a …
responsible for intestinal lesions. The multifactorial etiology attributed to CD includes a …
[HTML][HTML] Elevated apoptosis impairs epithelial cell turnover and shortens villi in TNF-driven intestinal inflammation
A Parker, L Vaux, AM Patterson, A Modasia… - Cell death & …, 2019 - nature.com
The intestinal epithelial monolayer, at the boundary between microbes and the host immune
system, plays an important role in the development of inflammatory bowel disease (IBD) …
system, plays an important role in the development of inflammatory bowel disease (IBD) …
[HTML][HTML] Recent advances in understanding inhibitor of apoptosis proteins
The inhibitor of apoptosis proteins (IAPs) are a family of proteins that were chiefly known for
their ability to inhibit apoptosis by blocking caspase activation or activity. Recent research …
their ability to inhibit apoptosis by blocking caspase activation or activity. Recent research …
Pathogenicity of Edwardsiella anguillarum to American eels (Anguilla rostrata) and RNA-seq analysis of host immune response to the E. anguillarum infection
Y Wang, S Zhai, Q Wan, M Xu, M Chen… - Fish & Shellfish …, 2023 - Elsevier
Edwardsiella anguillarum is a commonly pathogenic bacterium in cultivated eels, but its
pathogenicity to American eel (Anguilla rostrata) and the molecular mechanism of host anti …
pathogenicity to American eel (Anguilla rostrata) and the molecular mechanism of host anti …