The intestine serves as both our largest single barrier to the external environment and the
host of more immune cells than any other location in our bodies. Separating these potential …

Cyanidin-3-glucoside (C3G) is a well-known natural anthocyanin and possesses antioxidant
and anti-inflammatory properties. The catabolism of C3G in the gastrointestinal tract could …

During metastasis, cancer cells invade, intravasate, enter the circulation, extravasate, and
colonize target organs. Here, we examined the role of interleukin (IL)-22 in metastasis …

YT521-B homology domain family member 2 (YTHDF2) is an N6-methyladenosine (m6A)-
binding protein that was originally found to regulate the stability of mRNA. Growing evidence …

Simple Summary Tumor necrosis factor (TNF) receptor associated factor-2 (TRAF2) is an
intracellular adapter protein with E3 ligase activity, which interacts with a plethora of other …

The gut epithelium is a critical protective barrier. Its NAIP/NLRC4 inflammasome senses
infection by Gram-negative bacteria, including Salmonella Typhimurium (S. Tm) and …

Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract
responsible for intestinal lesions. The multifactorial etiology attributed to CD includes a …

The intestinal epithelial monolayer, at the boundary between microbes and the host immune
system, plays an important role in the development of inflammatory bowel disease (IBD) …

The inhibitor of apoptosis proteins (IAPs) are a family of proteins that were chiefly known for
their ability to inhibit apoptosis by blocking caspase activation or activity. Recent research …

Edwardsiella anguillarum is a commonly pathogenic bacterium in cultivated eels, but its
pathogenicity to American eel (Anguilla rostrata) and the molecular mechanism of host anti …