Rheumatoid arthritis in the elderly: characteristics and treatment considerations

L Serhal, MN Lwin, C Holroyd, CJ Edwards - Autoimmunity reviews, 2020 - Elsevier
The elderly rheumatoid arthritis (RA) population consists of both elderly-onset RA that
manifests after the age of 60 and individuals diagnosed with RA early in life who age …

The British Society for Rheumatology biologic DMARD safety guidelines in inflammatory arthritis

CR Holroyd, R Seth, M Bukhari, A Malaviya… - …, 2019 - academic.oup.com
Christopher R. Holroyd1, Rakhi Seth1, Marwan Bukhari2, Anshuman Malaviya3, Claire
Holmes1, Elizabeth Curtis4, Christopher Chan1, Mohammed A. Yusuf3, Anna Litwic4, 5 …

Anti-TNF therapy is associated with an increased risk of serious infections in patients with rheumatoid arthritis especially in the first 6 months of treatment: updated …

JB Galloway, KL Hyrich, LK Mercer, WG Dixon… - …, 2011 - academic.oup.com
Objectives. To evaluate the risk of serious infections (SIs) in patients with RA treated with
anti-TNF therapy with emphasis on the risk across different ages. Methods. Using data from …

Advanced age is an independent risk factor for severe infections and mortality in patients given anti–tumor necrosis factor therapy for inflammatory bowel disease

M Cottone, A Kohn, M Daperno, A Armuzzi… - Clinical …, 2011 - Elsevier
BACKGROUND & AIMS: Few data are available on effects of biologic therapies in patients
more than 65 years old with inflammatory bowel disease (IBD). We evaluated the risk and …

Rate of discontinuation and drug survival of biologic therapies in rheumatoid arthritis: a systematic review and meta-analysis of drug registries and health care …

A Souto, JR Maneiro, JJ Gomez-Reino - Rheumatology, 2016 - academic.oup.com
Objectives. To assess the proportion of RA patients who discontinued biologics in world
registries and health care databases and to identify causes and predictors of …

Systematic review with meta‐analysis: inflammatory bowel disease in the elderly

JP Gisbert, M Chaparro - Alimentary pharmacology & …, 2014 - Wiley Online Library
Background Elderly patients represent an increasing proportion of the inflammatory bowel
disease (IBD) population. Aim To critically review available data regarding the care of …

Safety of biologic therapy in older patients with immune-mediated diseases: a systematic review and meta-analysis

NZ Borren, AN Ananthakrishnan - Clinical gastroenterology and hepatology, 2019 - Elsevier
Background & Aims Management of immune-mediated inflammatory diseases often requires
lifelong immunosuppression. Increasing numbers of older patients have inflammatory …

The influence of ageing on the development and management of rheumatoid arthritis

AMH Boots, AB Maier, P Stinissen, P Masson… - Nature Reviews …, 2013 - nature.com
The population of elderly individuals with rheumatoid arthritis (RA) is expanding, due mainly
to increasing life expectancy. A variety of theories have been proposed to explain the ageing …

TNF‐α antagonist survival rate in a cohort of rheumatoid arthritis patients observed under conditions of standard clinical practice

A Marchesoni, E Zaccara, R Gorla… - Annals of the New …, 2009 - Wiley Online Library
A cohort of rheumatoid arthritis (RA) patients in the Lombardy Rheumatology Network
(LOHREN) registry and receiving anti‐TNF therapy was evaluated after 6, 12, 24, and 36 …

Measurement and rates of persistence with and adherence to biologics for rheumatoid arthritis: a systematic review

MA Blum, D Koo, JA Doshi - Clinical therapeutics, 2011 - Elsevier
BACKGROUND: Biologics are an important addition to the conventional care of patients with
rheumatoid arthritis (RA). Poor persistence with and adherence to biologics can undermine …