Peptide-based vaccines for tuberculosis

W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

A half-century of research on tuberculosis: Successes and challenges

BR Bloom - Journal of Experimental Medicine, 2023 - rupress.org
Great progress has been made over the past half-century, but TB remains a formidable
global health problem, particularly in low-and middle-income countries. Understanding the …

Key advances in vaccine development for tuberculosis—Success and challenges

R Lai, AF Ogunsola, T Rakib, SM Behar - NPJ vaccines, 2023 - nature.com
Breakthrough findings in the clinical and preclinical development of tuberculosis (TB)
vaccines have galvanized the field and suggest, for the first time since the development of …

Food for thought: addressing undernutrition to end tuberculosis

P Sinha, K Lönnroth, A Bhargava… - The Lancet Infectious …, 2021 - thelancet.com
Tuberculosis is the leading cause of deaths from an infectious disease worldwide. WHO's
End TB Strategy is falling short of several 2020 targets. Undernutrition is the leading …

Accelerating research and development of new vaccines against tuberculosis: a global roadmap

F Cobelens, RK Suri, M Helinski… - The Lancet Infectious …, 2022 - thelancet.com
To eliminate tuberculosis globally, a new, effective, and affordable vaccine is urgently
needed, particularly for use in adults and adolescents in low-income and middle-income …

The potential role of vaccines in preventing antimicrobial resistance (AMR): An update and future perspectives

V Costanzo, GN Roviello - Vaccines, 2023 - mdpi.com
In the modern era, the consumption of antibiotics represents a revolutionary weapon against
several infectious diseases, contributing to the saving of millions of lives worldwide …

[HTML][HTML] The potential clinical utility of measuring severe acute respiratory syndrome coronavirus 2-specific T-cell responses

D Goletti, L Petrone, D Manissero, A Bertoletti… - Clinical Microbiology …, 2021 - Elsevier
Background Both humoral and cell-mediated responses are associated with immunity to
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although our …

Controlled human infection models to accelerate vaccine development

RKM Choy, AL Bourgeois… - Clinical Microbiology …, 2022 - Am Soc Microbiol
The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

[HTML][HTML] Key recent advances in TB vaccine development and understanding of protective immune responses against Mycobacterium tuberculosis

TJ Scriba, MG Netea, AM Ginsberg - Seminars in immunology, 2020 - Elsevier
Tuberculosis is the leading infectious disease killer globally due to a single pathogen.
Despite wide deployment of standard drug regimens, modern diagnostics and a vaccine …

The road to elimination: current state of schistosomiasis research and progress towards the end game

P Ogongo, RK Nyakundi, GK Chege… - Frontiers in …, 2022 - frontiersin.org
The new WHO Roadmap for Neglected Tropical Diseases targets the global elimination of
schistosomiasis as a public health problem. To date, control strategies have focused on …