[HTML][HTML] Research advances for virus-vectored tuberculosis vaccines and latest findings on tuberculosis vaccine development

Z Hu, SH Lu, DB Lowrie, XY Fan - Frontiers in Immunology, 2022 - frontiersin.org
Tuberculosis (TB), caused by respiratory infection with Mycobacterium tuberculosis, remains
a major global health threat. The only licensed TB vaccine, the one-hundred-year-old Bacille …

[HTML][HTML] Vaccine development against tuberculosis over the last 140 years: Failure as part of success

SHE Kaufmann - Frontiers in Microbiology, 2021 - frontiersin.org
The year 2020 was shaped by the COVID-19 pandemic which killed more people than any
other infectious disease in this particular year. At the same time, the development of highly …

Tuberculosis in times of COVID-19

AJ Zimmer, JS Klinton, C Oga-Omenka… - J Epidemiol …, 2022 - jech.bmj.com
The COVID-19 pandemic has caused widespread disruptions to tuberculosis (TB) care and
service delivery in 2020, setting back progress in the fight against TB by several years. As …

[HTML][HTML] Vaccination against tuberculosis: revamping BCG by molecular genetics guided by immunology

SHE Kaufmann - Frontiers in immunology, 2020 - frontiersin.org
Tuberculosis (TB) remains a major health threat. Although a vaccine has been available for
almost 100 years termed Bacille Calmette-Guérin (BCG), it is insufficient and better vaccines …

[HTML][HTML] Vaccine development against tuberculosis before and after Covid-19

SHE Kaufmann - Frontiers in Immunology, 2023 - frontiersin.org
Coronavirus disease (Covid-19) has not only shaped awareness of the impact of infectious
diseases on global health. It has also provided instructive lessons for better prevention …

[HTML][HTML] Bioinformatics analysis and consistency verification of a novel tuberculosis vaccine candidate HP13138PB

P Cheng, F Jiang, G Wang, J Wang, Y Xue… - Frontiers in …, 2023 - frontiersin.org
Background With the increasing incidence of tuberculosis (TB) and the shortcomings of
existing TB vaccines to prevent TB in adults, new TB vaccines need to be developed to …

[HTML][HTML] Clinical development of new TB vaccines: recent advances and next steps

M Hatherill, RG White, TR Hawn - Frontiers in microbiology, 2020 - frontiersin.org
Mycobacterium tuberculosis (Mtb) kills more people worldwide than any single infectious
pathogen, yet the only vaccine licensed against tuberculosis, Bacille Calmette Guerin (BCG) …

[HTML][HTML] B-cells and antibodies as contributors to effector immune responses in tuberculosis

WF Rijnink, THM Ottenhoff, SA Joosten - Frontiers in immunology, 2021 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is still a major threat to
mankind, urgently requiring improved vaccination and therapeutic strategies to reduce TB …

[HTML][HTML] The cost and cost-effectiveness of novel tuberculosis vaccines in low-and middle-income countries: A modeling study

A Portnoy, RA Clark, M Quaife, CK Weerasuriya… - PLoS …, 2023 - journals.plos.org
Background Tuberculosis (TB) is preventable and curable but eliminating it has proven
challenging. Safe and effective TB vaccines that can rapidly reduce disease burden are …

[HTML][HTML] Immunotherapies against human bacterial and fungal infectious diseases: A review

H Qadri, AH Shah, M Alkhanani, A Almilaibary… - Frontiers in …, 2023 - frontiersin.org
Nations' ongoing struggles with a number of novel and reemerging infectious diseases,
including the ongoing global health issue, the SARS-Co-V2 (severe acute respiratory …