Mycobacterium tuberculosis (M. tb), a bacterial pathogen that causes tuberculosis disease
(TB), exerts an extensive burden on global health. The complex nature of M. tb, coupled with …

Adjuvant-containing subunit vaccines represent a promising approach for protection against
tuberculosis (TB), but current candidates require refrigerated storage. Here we present …

In addition to antibiotics, vaccination is considered among the most efficacious methods in
the control and the potential eradication of infectious diseases. New safe and effective …

Background Tuberculosis is a leading infectious cause of death worldwide. Novel vaccines
will be required to reach global targets and reverse setbacks resulting from the COVID-19 …

Background: Latent tuberculosis infection (LTBI) is the primary source of active tuberculosis
(ATB), but a preventive vaccine against LTBI is lacking. Methods: In this study, dominant …

Background India had an estimated 2.9 million tuberculosis cases and 506 thousand deaths
in 2021. Novel vaccines effective in adolescents and adults could reduce this burden …

Despite co-evolving with humans for centuries and being intensely studied for decades, the
immune correlates of protection against Mycobacterium tuberculosis (Mtb) have yet to be …

Tuberculosis (TB) is an airborne disease caused by Mycobacterium tuberculosis (Mtb).
Whilst a functional role for humoral immunity in Mtb protection remains poorly defined …

The tuberculosis (TB) vaccine Bacillus Calmette‐Guérin (BCG) was introduced 100 years
ago, but as it provides insufficient protection against TB disease, especially in adults, new …

BACKGROUND Vaccination is typically administered without regard to site of prior
vaccination, but this factor may substantially affect downstream immune responses …