Tuberculosis (TB) is a global health threat, killing approximately 1.5 million people each
year. The eradication of Mycobacterium tuberculosis, the main causative agent of TB, is …

A crisis in bacterial infections looms as ageing populations, increasing rates of bacteraemia
and healthcare-associated infections converge with increasing antimicrobial resistance and …

The advent and use of antimicrobials have played a key role in treating potentially life‐
threatening infectious diseases, improving health, and saving the lives of millions of people …

Effects of Infection on Natural Immunity Antigen-nonspecific host defenses are altered by
infections, with epigenetic changes in the effector cells of natural immunity. Some of these …

The mechanisms by which antibodies confer protection vary across vaccines, ranging from
simple neutralization to functions requiring innate immune recruitment via Fc-dependent …

结核病从1882 年发现至今已有100 多年历史, 是全球前10 名死亡原因之一. 2019
年全球范围内估计有1000 万人罹患结核病, 男性多于女性; 在全球结核病患者中, 年龄在15 …

Mycobacterium tuberculosis (Mtb) causes the human disease tuberculosis (TB) and remains
the top global infectious pandemic after coronavirus disease 2019 (COVID-19). Furthermore …

Key Clinical Points Latent Tuberculosis Infection Prevention of progression from latent
tuberculosis infection (LTBI) to tuberculosis disease is an important individual and public …

Tuberculosis (TB) remains a serious public health threat around the world. An effective
vaccine is urgently required for cost-effective, long-term control of TB. However, the only …

Objectives The development of non‐sputum‐based assays for tuberculosis (TB) diagnosis
and treatment monitoring is a key priority. Recent data indicate that whole blood‐based …