The diversity outbred mouse population is an improved animal model of vaccination against tuberculosis that reflects heterogeneity of protection
Many studies of Mycobacterium tuberculosis infection and immunity have used mouse
models. However, outcomes of vaccination and challenge with M. tuberculosis in inbred …
models. However, outcomes of vaccination and challenge with M. tuberculosis in inbred …
A tuberculosis epidemic model as a proxy for the assessment of the novel M72/AS01E vaccine
Tuberculosis (TB) is a bacterial infectious disease that comes with a high mortality rate
through manifesting lung damage. Understanding the TB transmission is critical to designing …
through manifesting lung damage. Understanding the TB transmission is critical to designing …
[HTML][HTML] Tuberculosis vaccines in the era of Covid-19–what is taking us so long?
HM Dockrell, H McShane - EBioMedicine, 2022 - thelancet.com
The Mycobacterium bovis BCG vaccine was first used in 1921, but has not controlled the
global spread of tuberculosis (TB). There are still no new licensed tuberculosis vaccines …
global spread of tuberculosis (TB). There are still no new licensed tuberculosis vaccines …
New tuberculosis vaccines: advances in clinical development and modelling
Tuberculosis remains a major source of morbidity and mortality worldwide, with 10 million
cases and 1.5 million deaths in 2018. Achieving 'End TB'prevention and care goals by 2035 …
cases and 1.5 million deaths in 2018. Achieving 'End TB'prevention and care goals by 2035 …
[HTML][HTML] Towards new TB vaccines
B Brazier, H McShane - Seminars in immunopathology, 2020 - Springer
Mycobacterium tuberculosis remains the leading cause of death attributed to a single
infectious organism. Bacillus Calmette-Guerin (BCG), the standard vaccine against M …
infectious organism. Bacillus Calmette-Guerin (BCG), the standard vaccine against M …
[HTML][HTML] A Structural View at Vaccine Development against M. tuberculosis
M Romano, F Squeglia, E Kramarska, G Barra… - Cells, 2023 - mdpi.com
Tuberculosis (TB) is still the leading global cause of death from an infectious bacterial agent.
Limiting tuberculosis epidemic spread is therefore an urgent global public health priority. As …
Limiting tuberculosis epidemic spread is therefore an urgent global public health priority. As …
HIV-Associated Tuberculosis
G Meintjes, G Maartens - New England Journal of Medicine, 2024 - Mass Medical Soc
Key Points HIV-Associated Tuberculosis Almost half of inpatients with human
immunodeficiency virus (HIV)–associated tuberculosis in countries with a high disease …
immunodeficiency virus (HIV)–associated tuberculosis in countries with a high disease …
Estimation of the global burden of Mycobacterium tuberculosis lineage 1
T Netikul, P Palittapongarnpim… - Infection, Genetics and …, 2021 - Elsevier
Tuberculosis is still problematic as it affects large numbers of people globally.
Mycobacterium tuberculosis Lineage 1 (L1) or Indo Oceanic Lineage, one of widespread …
Mycobacterium tuberculosis Lineage 1 (L1) or Indo Oceanic Lineage, one of widespread …
[HTML][HTML] Management of latent tuberculosis infection in China: Exploring solutions suitable for high-burden countries
X Cui, L Gao, B Cao - International Journal of Infectious Diseases, 2020 - Elsevier
China is one of the countries with a high burden of tuberculosis (TB) and latent tuberculosis
infection (LTBI). It was recently estimated that China had the highest LTBI burden in the …
infection (LTBI). It was recently estimated that China had the highest LTBI burden in the …
[HTML][HTML] Leveraging antibody, B cell and Fc receptor interactions to understand heterogeneous immune responses in tuberculosis
SM Carpenter, LL Lu - Frontiers in immunology, 2022 - frontiersin.org
Despite over a century of research, Mycobacterium tuberculosis (Mtb), the causative agent of
tuberculosis (TB), continues to kill 1.5 million people annually. Though less than 10% of …
tuberculosis (TB), continues to kill 1.5 million people annually. Though less than 10% of …