[HTML][HTML] Advances in immunotherapy for triple-negative breast cancer

Y Liu, Y Hu, J Xue, J Li, J Yi, J Bu, Z Zhang, P Qiu… - Molecular cancer, 2023 - Springer
Background Immunotherapy has recently emerged as a treatment strategy which stimulates
the human immune system to kill tumor cells. Tumor immunotherapy is based on immune …

Resveratrol: biology, metabolism, and detrimental role on the tumor microenvironment of colorectal cancer

B Dariya, BP Girish, N Merchant, M Srilatha… - Nutrition …, 2023 - academic.oup.com
A substantial increase in colorectal cancer (CRC)–associated fatalities can be attributed to
tumor recurrence and multidrug resistance. Traditional treatment options, including radio …

[HTML][HTML] Therapeutic potential of tumor metabolic reprogramming in triple-negative breast cancer

G Munkácsy, L Santarpia, B Győrffy - International Journal of Molecular …, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, with
clinical features of high metastatic potential, susceptibility to relapse, and poor prognosis …

[HTML][HTML] Dynamic interactions in the tumor niche: how the cross-talk between CAFs and the tumor microenvironment impacts resistance to therapy

O Piwocka, I Piotrowski, WM Suchorska… - Frontiers in Molecular …, 2024 - frontiersin.org
The tumor microenvironment (TME) is a complex ecosystem of cells, signaling molecules,
and extracellular matrix components that profoundly influence cancer progression. Among …

Unraveling the tumor microenvironment: insights into cancer metastasis and therapeutic strategies

M El-Tanani, SA Rabbani, R Babiker, I Rangraze… - Cancer Letters, 2024 - Elsevier
This comprehensive review delves into the pivotal role of the tumor microenvironment (TME)
in cancer metastasis and therapeutic response, offering fresh insights into the intricate …

Cytokines and soluble mediators as architects of tumor microenvironment reprogramming in cancer therapy

S Xu, Q Wang, W Ma - Cytokine & Growth Factor Reviews, 2024 - Elsevier
Navigating the intricate landscape of the tumor microenvironment (TME) unveils a pivotal
arena for cancer therapeutics, where cytokines and soluble mediators emerge as double …

The metabolic syndrome, a human disease

M Alemany - International journal of molecular sciences, 2024 - mdpi.com
This review focuses on the question of metabolic syndrome (MS) being a complex, but
essentially monophyletic, galaxy of associated diseases/disorders, or just a syndrome of …

Engineering heterogeneous tumor models for biomedical applications

Z Wu, D Huang, J Wang, Y Zhao, W Sun… - Advanced …, 2024 - Wiley Online Library
Tumor tissue engineering holds great promise for replicating the physiological and
behavioral characteristics of tumors in vitro. Advances in this field have led to new …

[HTML][HTML] The role of cancer-associated fibroblasts in bladder cancer progression

L Huang, Q Xie, J Deng, WF Wei - Heliyon, 2023 - cell.com
Cancer-associated fibroblasts (CAFs) are key stromal cells in the tumor microenvironment
(TME) that critically contribute to cancer initiation and progression. In bladder cancer (BCa) …

Analysis of immune resistance mechanisms in TNBC: dual effects inside and outside the tumor

J Xu, C Gan, S Yu, S Yao, W Li, H Cheng - Clinical Breast Cancer, 2023 - Elsevier
Triple-negative breast cancer (TNBC) is a unique subtype of breast cancer characterized by
the lack of expression of the estrogen receptor, progesterone receptor, and human …