Chronic exposure to indoor biomass smoke from the combustion of solid organic fuels is a
major cause of disease burden worldwide. Almost 3 billion people use solid fuels such as …

Several mAbs have been tested or are currently under clinical evaluation for the treatment of
COPD. They can be subdivided into those that aim to block specific pro-inflammatory and …

Rationale COPD is characterized by chronic airway inflammation, small airways changes,
with disappearance and obstruction, and also distal/alveolar destruction (emphysema). The …

Interleukin (IL)-18, a member of the IL-1 family of alarmins, is abundantly released in the
lungs following influenza A (IAV) infections yet its role in orchestrating the local adaptive …

Purpose Neutrophilic asthma is associated with asthma exacerbation, steroid insensitivity,
and severe asthma. Interleukin (IL)-24 is overexpressed in asthma and is involved in the …

Background Chronic obstructive pulmonary disease (COPD) is defined by persistent airway
and lung inflammation, excessive mucus production, remodeling of the airways, and …

The effect of air pollution on public health is severely detrimental. In humans; the
physiological response against pollutants is mainly elicited via the activation of aryl …

Biomass exposure is a significant environmental risk factor for COPD, but the underlying
mechanisms have not yet been fully elucidated. Inflammatory microenvironment has been …

Epididymitis is an epididymal inflammation that may lead to male infertility. Dendritic cells
(DCs) and myeloid differentiation primary response gene 88 (Myd88) were associated with …

Spondyloarthritis (SpA) encompasses a group of chronic inflammatory rheumatic diseases
with a predilection for the spinal and sacroiliac joints, which include axial spondyloarthritis …