Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Recent developments of carbon dots in biosensing: A review

C Ji, Y Zhou, RM Leblanc, Z Peng - ACS sensors, 2020 - ACS Publications
Early diagnosis of diseases is of great importance because it increases the chance of a cure
and significantly reduces treatment costs. Thus, development of rapid, sensitive, and reliable …

Metal–organic framework-functionalized paper-based electrochemical biosensor for ultrasensitive exosome assay

X Liu, X Gao, L Yang, Y Zhao, F Li - Analytical chemistry, 2021 - ACS Publications
The exosome has emerged as a promising noninvasive biomarker for the early diagnosis of
cancer. Therefore, it is highly desirable to develop simple, inexpensive, and user-friendly …

Materials with tunable optical properties for wearable epidermal sensing in health monitoring

F Han, T Wang, G Liu, H Liu, X Xie, Z Wei… - Advanced …, 2022 - Wiley Online Library
Advances in wearable epidermal sensors have revolutionized the way that physiological
signals are captured and measured for health monitoring. One major challenge is to convert …

[HTML][HTML] Nanotechnology in cancer diagnosis: progress, challenges and opportunities

Y Zhang, M Li, X Gao, Y Chen, T Liu - Journal of hematology & oncology, 2019 - Springer
In the fight against cancer, early detection is a key factor for successful treatment. However,
the detection of cancer in the early stage has been hindered by the intrinsic limits of …

Nucleic acid aptamers for molecular diagnostics and therapeutics: advances and perspectives

L Li, S Xu, H Yan, X Li, HS Yazd, X Li… - Angewandte Chemie …, 2021 - Wiley Online Library
The advent of SELEX (systematic evolution of ligands by exponential enrichment)
technology has shown the ability to evolve artificial ligands with affinity and specificity able to …

Plasmonic alloys reveal a distinct metabolic phenotype of early gastric cancer

H Su, X Li, L Huang, J Cao, M Zhang… - Advanced …, 2021 - Wiley Online Library
Gastric cancer (GC) is a multifactorial process, accompanied by alterations in metabolic
pathways. Non‐invasive metabolic profiling facilitates GC diagnosis at early stage leading to …

In Situ Formation of Gold Nanoparticles Decorated Ti3C2 MXenes Nanoprobe for Highly Sensitive Electrogenerated Chemiluminescence Detection of Exosomes …

H Zhang, Z Wang, F Wang, Y Zhang, H Wang… - Analytical …, 2020 - ACS Publications
In this work, an ultrasensitive electrogenerated chemiluminescence (ECL) biosensor for
exosomes and their surface proteins was developed by the in situ formation of gold …

Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers

C Liu, J Zhao, F Tian, L Cai, W Zhang, Q Feng… - Nature biomedical …, 2019 - nature.com
Non-invasive assays for early cancer screening are hampered by challenges in the isolation
and profiling of circulating biomarkers. Here, we show that surface proteins from serum …

[HTML][HTML] Detection and beyond: Challenges and advances in aptamer-based biosensors

H Yoo, H Jo, SS Oh - Materials Advances, 2020 - pubs.rsc.org
Beyond traditional needs of biosensors such as high sensitivity and selectivity for analyte
detection, newly emerging requirements including a real-time detection ability and in-field …