Microfluidics embedded with microelectrodes for electrostimulation of neural stem cells proliferation

Q Li, B Kang, L Wang, T Chen, Y Zhao, S Feng… - Chinese Chemical …, 2022 - Elsevier
The regeneration of the injured nerve and recovery of its function have brought attention in
the medical field. Electrical stimulation (ES) can enhance the cellular biological behavior …

Single-cell enzyme-free dissociation of neurospheres using a microfluidic chip

CH Lin, DC Lee, HC Chang, IM Chiu… - Analytical chemistry, 2013 - ACS Publications
Obtaining single dissociated cells from neurospheres is difficult using nonenzymatic
methods. In this paper we report the development of a microfluidic-chip-based approach that …

3D-cultured neural stem cell microarrays on a micropillar chip for high-throughput developmental neurotoxicology

P Joshi, KN Yu, SY Kang, SJ Kwon, PS Kwon… - Experimental Cell …, 2018 - Elsevier
Numerous chemicals including environmental toxicants and drugs have not been fully
evaluated for developmental neurotoxicity. A key gap exists in the ability to predict …

Directional migration and differentiation of neural stem cells within three-dimensional microenvironments

A Shamloo, M Heibatollahi, MRK Mofrad - Integrative biology, 2015 - academic.oup.com
Harnessing neural stem cells to repair neuronal damage is a promising potential treatment
for neuronal diseases. To enable future therapeutic efficacy, the survival, proliferation …

Hydrophobic patterning‐based 3D microfluidic cell culture assay

S Han, J Kim, R Li, A Ma, V Kwan… - Advanced …, 2018 - Wiley Online Library
Engineering physiologically relevant in vitro models of human organs remains a
fundamental challenge. Despite significant strides made within the field, many promising …

[HTML][HTML] The effect of amino density on the attachment, migration, and differentiation of rat neural stem cells in vitro

HL Li, H Zhang, H Huang, ZQ Liu, YB Li, H Yu, YH An - Molecules and cells, 2013 - Elsevier
Artificial extracellular matrices play important roles in the regulation of stem cell behavior. To
generate materials for tissue engineering, active functional groups, such as amino, carboxyl …

Hydrogel-integrated microfluidic systems for advanced stem cell engineering

S An, SY Han, SW Cho - BioChip Journal, 2019 - Springer
Previous culture techniques are often ineffective for providing appropriate conditions to cells
grown in vitro for efficient growth and maturation. However, the advent of microfluidic chips …

[HTML][HTML] Microfluidics as efficient technology for the isolation and characterization of stem cells

A Aghlmandi, A Nikshad, R Safaralizadeh… - EXCLI …, 2021 - ncbi.nlm.nih.gov
The recent years have been passed with significant progressions in the utilization of
microfluidic technologies for cellular investigations. The aim of microfluidics is to mimic small …

[HTML][HTML] A 3D-printed microbial cell culture platform with in situ PEGDA hydrogel barriers for differential substrate delivery

AL Kadilak, JC Rehaag, CA Harrington, LM Shor - Biomicrofluidics, 2017 - pubs.aip.org
Additive manufacturing, or 3D-printing techniques have recently begun to enable simpler,
faster, and cheaper production of millifluidic devices at resolutions approaching 100–200 …

Stem cells and liver engineering

L Ordovás, Y Park, CM Verfaillie - Biotechnology advances, 2013 - Elsevier
Human hepatocytes, suitable for treatment of patients with liver failure, for the creation of
bioartificial (BAL) devices, or for studies for toxicity and metabolization studies in the …