Leishmania treatment and prevention: Natural and synthesized drugs

AA Bekhit, E El-Agroudy, A Helmy, TM Ibrahim… - European journal of …, 2018 - Elsevier
Leishmaniasis affects over 150 million people all over the world, especially in subtropical
regions. Currently used antileishmanial synthesized drugs are associated with some …

[HTML][HTML] Revisiting nature: a review of iridoids as a potential antileishmanial class

G Arraché Gonçalves, VL Eifler-Lima… - Phytochemistry …, 2022 - Springer
Leishmaniasis still stands as one of the most prevalent neglected tropical diseases in the
least developed and emerging countries. The recommended therapeutic arsenal to treat …

[HTML][HTML] Polarity directed optimization of phytochemical and in vitro biological potential of an indigenous folklore: Quercus dilatata Lindl. ex Royle

M Ahmed, H Fatima, M Qasim, B Gul - BMC complementary and …, 2017 - Springer
Background Plants have served either as a natural templates for the development of new
chemicals or a phytomedicine since antiquity. Therefore, the present study was aimed to …

[HTML][HTML] In vitro antileishmanial and antitrypanosomal activity of compounds isolated from the roots of Zanthoxylum tingoassuiba

RS Costa, OP Souza Filho, OCS Dias… - Revista Brasileira de …, 2018 - SciELO Brasil
Abstract Five coumarins (5, 7, 8-trimethoxycoumarin (1), sabandin (2), cubreuva lactone (3),
5, 7-dimethoxycoumarin (5) and braylin (6)), seven furoquinoline alkaloids (isopimpinelin …

Evaluation of the In Vitro Antiplasmodial, Antileishmanial, and Antitrypanosomal Activity of Medicinal Plants Used in Saudi and Yemeni Traditional Medicine

RA Mothana, NM Al-Musayeib… - Evidence‐Based …, 2014 - Wiley Online Library
The antiplasmodial, antileishmanial, and antitrypanosomal activity of twenty‐five medicinal
plants distributed in Saudi Arabia and Yemen was evaluated. The plants were extracted with …

[HTML][HTML] Antileishmanial potential of tropical rainforest plant extracts

L Monzote, A Piñón, WN Setzer - Medicines, 2014 - mdpi.com
A total of 115 different plant extracts from our collection, representing 96 plant species, have
been evaluated for in vitro antileishmanial activity against L. amazonensis promastigotes. In …

[HTML][HTML] Synthesis, spectroscopic characterization, antileishmanial, DNA binding, antioxidant, cytotoxicity, antifungal and antibacterial studies of organotin (IV) …

S Hussain, S Shujah, A Rehman, ST Hussain… - Arabian Journal of …, 2023 - Elsevier
Six new organotin (IV) complexes,[Bu 2 SnL](1),[Me 2 SnL](2),[Me 3 SnL](3),[Bu 3
SnL](4),[Ph 3 SnL](5) and [(n-Oct 2 SnL](6) have been synthesized from the reaction of 4-((5 …

New flavonol methyl ether from the leaves of Vitex peduncularis exhibits potential inhibitory activity against Leishmania donovani through activation of iNOS …

P Rudrapaul, IS Sarma, N Das, UC De… - European journal of …, 2014 - Elsevier
One new flavonol methyl ether (1), along with four known compounds from the leaves of
methanol extract of Vitex peduncularis Wall and three known compounds from the leaves of …

[HTML][HTML] Myrsinoic acid B from Myrsine coriacea reverses depressive-like behavior and brain oxidative stress in streptozotocin-diabetic rats

PL Zimath, AP Dalmagro, LM da Silva… - Chemico-Biological …, 2021 - Elsevier
Aims Major depressive disorder (MDD) affects approximately 322 million people worldwide
and is a common comorbidity in patients with diabetes mellitus (DM). A possible …

[HTML][HTML] In vitro evaluation of traditionally used Surinamese medicinal plants for their potential anti-leishmanial efficacy

DRA Mans, T Beerens, I Magali, RC Soekhoe… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance Plant-based preparations are extensively used in
Surinamese folk medicine for treating leishmaniasis, but often without a scientific rationale …