Growing evidence suggests that aberrant epigenetic regulation of gene function is strongly
related to the genesis of cancer. Unlike genetic mutations, the ability to reprogram the …

The global burden of breast cancer (BC) is increasing significantly. This trend is caused by
several factors such as late diagnosis, limited treatment options for certain BC subtypes …

Metastatic prostate cancer remains a major clinical challenge and metastatic lesions are
highly heterogeneous and difficult to biopsy. Liquid biopsy provides opportunities to gain …

Epigenetic modifications play important roles in regulating carcinogenesis, and specific
epigenetic modifications have emerged as potential tumor markers. Herein, we summarize …

Prostate cancer (PCa) is the most prevalent urological cancer that affects aging men in
South Africa, and mechanisms underlying prostate tumorigenesis remain elusive. Research …

Radiotherapy (RT) is one of the mainstay treatments for prostate cancer (PCa), a highly
prevalent neoplasm among males worldwide. About 30% of newly diagnosed PCa patients …

Metastases from primary prostate cancers to rare locations, such as the brain, are becoming
more common due to longer life expectancy resulting from improved treatments. Epigenetic …

Modified epigenetic programming early in life is proposed to underlie the development of an
adverse adult phenotype, known as the Developmental Origins of Health and Disease …

Prostate cancer (PCa) is the most commonly diagnosed malignant neoplasm in men in the
Western world. Localized low-risk PCa has an excellent prognosis thanks to effective local …

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological cancer
characterized by skewed epigenetic patterns, raising the possibility of therapeutically …