Clinical implementation of pharmacogenomics (PGx) leads to personalized medicine, which
improves the efficacy, safety, and cost-effectiveness of treatments. Although PGx-based …

Non-small-cell lung cancer is often diagnosed at the metastatic stage, with median survival
of just 1 year. The identification of driver mutations in the epidermal growth factor receptor …

Pharmacogenomics (PGx) studies the use of genetic data to optimize drug therapy.
Numerous clinical centers have commenced implementing pharmacogenetic tests in clinical …

The big data revolution is making vast amounts of information available in all sectors of the
economy including health care. One important type of data that is particularly relevant to …

Pharmacogenomics is a study of how the genome background is associated with drug
resistance and how therapy strategy can be modified for a certain person to achieve benefit …

Purpose Preemptive pharmacogenetic testing aims to optimize medication use by having
genetic information at the point of prescribing. Payers' decisions influence implementation of …

There is considerable interindividual variability in the response to antiplatelet and
anticoagulant therapies, and this variation may be attributable to genetic variants. There has …

Pharmacogenomics and personalized medicine interventions hold promise to optimize drug
treatment modalities and hence, improve the quality of life of the patients by minimizing the …

Objective Pharmacogenomics seeks to improve prescribing by reducing drug
inefficacy/toxicity. However, views of patients during pharmacogenomic-guided care are …

Objectives Implementing new programs to support precision medicine in clinical settings is a
complex endeavor. We describe challenges and potential solutions based on the Indiana …