This innovative study charts the beginnings, history and fate of Interferon-one of modern
medicine's most famous and infamous drugs. Interferon is part of the medical profession's …

A newly discovered E3 ubiquitin ligase, UBR7, plays a crucial role in histone H2BK120
monoubiquitination. Here, we report a novel function of UBR7 in promoting hepatitis B virus …

Human fibroblast interferon (F-interferon) purified by adsorption on controlled-pore glass
was given intramuscularly to patients at daily dosages of up to 20× 106 units. Serum levels …

In 1929 GM Findlay published a moderate sized book entitled" Recent Advances in
Chemotherapy". It dealt mainly with trypanosomes, malaria and amoebae with smaller …

Panicum antidotale has traditionally been used as a poultice to alleviate local inflammation
and painful diseases. This study aimed to evaluate the anti-inflammatory, wound-healing …

Chronic HBV infection is a major cause of liver disease and cancer worldwide. Approaches
for cure are lacking, and the knowledge of virus-host interactions is still limited. Here, we …

In a double-blind study human leucocyte interferon was given for six weeks to 8 of 16
patients with chronic HBsAg-positive hepatitis. In the first week 12× 10 6 reference units …

In an uncontrolled trial, 29 patients with chronic hepatitis B virus infection were treated with
93 courses of adenine arabinoside at doses ranging from 2.5 to 15 mg/kg per day. Most …

Nine patients with chronic type B hepatitis were entered into a preliminary study of
recombinant, human α-interferon therapy. Patients received one to four courses of Interferon …

Eighteen patients who developed varicella while being treated for malignancy received
human leukocyte interferon in a randomized double-blind placebo-controlled trial …