Eighteen patients who developed varicella while being treated for malignancy received
human leukocyte interferon in a randomized double-blind placebo-controlled trial …

Human fibroblast interferon (F-interferon) purified by adsorption on controlled-pore glass
was given intramuscularly to patients at daily dosages of up to 20× 106 units. Serum levels …

In June 1993 a clinical trial of fialuridine (FIAU), a promising new medication for hepatitis B,
was abruptly terminated when one of the 15 out-patients participating in the National …

The roles of RNA sequence/structure motifs, Packaging Signals (PSs), for regulating
assembly of an HBV genome transcript have been investigated in an efficient in vitro assay …

Viral diseases are among the leading causes of human illness throughout the world,
exacting a major toll in personal suffering and exerting a significant economic impact due to …

Many drugs have been used in the treatment of chronic hepatitis B, but with the exception of
interferon, none have proved to be effective. Several studies have found that a sustained …

A double-blind trial of (+)-cyanidanol-3 (2 g/day) versus placebo tablets was carried out in
100 patients with acute viral hepatitis. 51 received the drug and 49 placebo.(+)-Cyanidanol …

Interferons (IFN) elicit antiviral and antineoplastic activities by binding to specific receptors
on the cell surface. The binding characteristics of IFN to human lymphocytes were studied …

Large doses of recombinant leukocyte A interferon were administered to 20 patients with
deoxyribonucleic acid polymerase-and hepatitis B e antigen positive chronic hepatitis B to …

Objective: To determine markers predictive of effective interferon treatment for patients with
chronic hepatitis C virus (HCV) infection, we studied 80 Japanese patients treated for 6 …